NCT07315984Not yet recruiting
Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
The objective of the study is to validate the use of wearable sensors and digital health technologies for monitoring disease activity in Huntington's Disease (HD). Healthy subjects, as well as subjects with documented diagnosis of HD will be screened and recruited at University of Rochester Medical Center and Vanderbilt University Medical Center to participate in this 12-month observational study. There will be a total of 5 visits every approximately 3 months. In each study visit, participants will complete several Patient Reported Outcomes (PROs), Clinical Reported Outcomes, complete a series of Digital Assessments (Speech, Cognitive, Motor, and Finger Tapping). Participants will be provided with a pendant, wrist, and ankle sensors to monitor their daily physical activities for 7 days after each study visit. Participants will also be provided with a tablet to complete digital assessments (Speech, Cognitive, Motor, and Finger Tapping) on monthly basis at home.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 75 (estimated)
- First submitted
- 30 Dec 2025
- Start date
- 31 Jan 2027
- Primary completion date
- 31 Aug 2028
- Lead sponsor
- BioSensics
- Diseases
- Huntington's disease
- NCT number
- NCT07315984
What you commit to
- Study type: Observational
- Planned participants: 75
- From 31 Jan 2027 to the primary completion date, 31 Aug 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals with a neurological, medical, or psychiatric condition that, in the investigator's judgment, would interfere with safe participation in study activities.
Other
- Diagnosis of juvenile-onset HD.
- Individuals who are non-ambulatory.
- Montreal Cognitive Assessment (MoCA) score of 18 or lower
- Pregnant individuals, due to potential changes in gait and physical activity during pregnancy.
- Cannot be enrolled into a blinded intervention trial at baseline.
Who the study is looking for
- Male or female, aged 25-65 years
- For HD participants: Genetically diagnosed with HD
- Fluent in English (able to speak and read).
- Ambulatory without the need for a walking aid.
- Able to independently perform all study activities safely, as determined by the investigator.
- Willing and able to provide informed consent and comply with all study procedures.
- For control participants:
- Male or female, aged 25-65 years
- Clinically assessed to be in good health, with no evidence of neurological disorders that could cause involuntary movements or gait disturbances
Age in the registry: 25 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| University of Rochester Medical Center Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.