Efficacy of Adaptive, Gamified Digital Therapeutics Intervention for Individuals With Methamphetamine Use Disorder in Community Rehabilitation
Key facts
- Who runs it
- Adai Technology (Beijing) Co., Ltd.
- Where
- China1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 360 people enrolled
- Started
- 1 Jun 2025
- Ended
- 2 Nov 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- WonderLab Harbor+ (Adaptive DTx)
- Standard Community Counseling
- Record updated
- 29 October 2026
Who can take part
- Age
- 18 years to 60 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Age between 18 and 60 years
- Currently enrolled in a community rehabilitation program
- Ability to fluently operate a smartphone (Android or iOS)
Who cannot take part
- Presence of a severe mental health condition (e.g., schizophrenia, bipolar I disorder) requiring acute psychiatric care
- Inability to provide informed consent
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
This study evaluates the efficacy of a comprehensive, adaptive digital therapeutics (DTx) smartphone application compared to treatment as usual (TAu) for individuals with Methamphetamine Use Disorder (MUD) receiving community-based rehabilitation. The intervention integrates Internet-based Cognitive Behavioral Therapy (ICBT), adaptive Approach Bias Modification (A-ApBM), cognitive training, and contingency management. The primary hypothesis is that the DTx intervention will result in a greater reduction in cue-induced craving compared to standard community care.
The 2 groups in the trial
- Adaptive Digital Therapeutics (DTx)Treatment being tested
Participants receive access to WonderLab Harbor+ (Adaptive DTx), a smartphone application, for 8 weeks. They are instructed to complete one ICBT session per week (approx. 10 mins) and one Adaptive Approach Bias Modification (A-ApBM) session daily (approx. 3 mins). The app also includes cognitive training games and a rewards system (Contingency Management). This is provided in addition to standard community care.
Treatment: WonderLab Harbor+ (Adaptive DTx)
- Treatment as Usual (TAU)Existing treatment, for comparison
Participants receive standard care provided by the community rehabilitation centers, which consists of counseling sessions (in-person or telephone) delivered by social workers covering stress management, family issues, and craving suppression.
Treatment: Standard Community Counseling
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Efficacy of an Adaptive, Gamified Digital Therapeutics Intervention for Individuals With Methamphetamine Use Disorder in Community Rehabilitation: A Pragmatic Randomized Controlled Trial
- Record updated
- 29 October 2026