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Physical activity and fertility treatment outcomes in women with infertility

Looks at how physical activity relates to pregnancy in women having fertility treatment.

Key facts

Who runs it
University Hospital, Basel, Switzerland
Where
Switzerland1 site in 1 countryChoose a country to see its sites
Trial code
Registry title
Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medically Assisted Reproduction
Status
Recruiting
People taking part
115 people, planned
Started
16 Jan 2026
Expected to end
Jan 2030
Type of study
Observational
Treatments tested
  • Health, fitness and lifestyle assessment
Record updated
21 January 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women aged 18 to 43 who plan to have medically assisted reproduction, such as IUI, IVF or ICSI. It studies how physical activity, fitness and health relate to getting pregnant.

Age
18 to 43 years
Sex
Women only
Disease stage
Women with infertility who plan to have medically assisted reproduction (MAR), for example IUI, IVF or ICSI.

Main reasons for not taking part

  • Health problems that would stop hormone treatment for MAR, or that would stop a cycling exercise test (CPET).
  • Current illegal drug use, including daily marijuana or CBD. Up to 2 alcoholic drinks per day are allowed.
  • Severe long-term disease, such as severe heart failure or active cancer.
  • Severe kidney problems (for example eGFR <30 ml/min/m2), liver cirrhosis or other severe liver damage.
  • Uncontrolled thyroid problems or uncontrolled high blood pressure. Not able to follow the study steps, for example because of language problems.

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Voluntary written informed consent of the participant has been obtained prior to any screening procedures
  • Age 18-43
  • Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET)

Who cannot take part

  • Absolute and relative contraindications for cardiopulmonary exercise testing (CPET) - No pregnancy at initial screening - Current illicit drug abuse including daily marijuana and CBD consumption (alcohol ≤2 drinks per day allowed)
  • Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease)
  • Severe renal impairment (e.g. estimated glomerular filtration rate <30 ml/min/m2)
  • Known liver cirrhosis or other severe liver impairment
  • Uncontrolled hypertension
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, etc
  • Any reduction in general state of health preventing from performing hormonal stimulation for MAR
  • Uncontrolled dysthyroidism

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 43 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction. Additionally, it evaluates how cardiorespiratory fitness, cardiovascular health, psychosocial factors, sleep quality, stress, and cognitive function relate to reproductive outcomes.

Treatments tested

  • Health, fitness and lifestyle assessment

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medically Assisted Reproduction
Plain-language title
Physical activity and fertility treatment outcomes in women with infertilityGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Fit questions
Built from NCT07321665, who can take part
Record updated
21 January 2026