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The Effectiveness of a Herbal Supplement in Osteoarthritis.

Key facts

Who runs it
Middlesex University
Where
United Kingdom1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
30 people, planned
Started
5 Dec 2025
Planned end
Sept 2026
Type of study
Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
Treatments tested
  • Active treatment
  • Placebo
Record updated
29 January 2026

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 16 criteriaShow less

Who can take part

  • Aged ≥ 18
  • Diagnosis of osteoarthritis in knee or hip
  • Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours
  • Lequesne's Functional Index (LFI) score ≥ 7
  • Ambulant patient

Who cannot take part

  • Expectation of surgery
  • Use of concomitant medication able to interfere with the interventions
  • Autoimmune disease such as rheumatoid arthritis, gout, lupus
  • Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage
  • History of the viscous or corticosteroids injections into affected joints or oral corticosteroids within last 12 months
  • Allergy to one of the intervention's ingredients or NSAIDs
  • Peptic ulceration and upper gastrointestinal haemorrhage
  • High alcohol intake, inability to abstain from alcohol, substance abuse, history of addiction
  • Tumor, cancer
  • Pregnant and breastfeeding
  • Abnormal renal or/and hepatic functions or altered blood chemistry

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis.

Read full original descriptionShow less

The primary objective is to determine whether the supplement improves osteoarthritis-related symptoms.

The supplement will be compared with a placebo.

Participants will:

* take the supplement and placebo for 4 weeks each, one at a time; * complete validated questionnaires (6 times online) * perform three performance-based physical tests (6 times online) * provide a urine sample

The 2 groups in the trial

  • Active TreatmentTreatment being tested

    Dietary supplement containing standardised herbal extracts of Boswellia Serrata (525 mg), Curcuma Longa (150 mg), Vitis vinifera (75 mg)

  • PlaceboPlacebo, for comparison

    Dietary supplement placebo containing no standardised herbal extracts or other active ingredients.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Effectiveness of a Herbal Supplement Containing Boswellia Serrata, Curcuma Longa, and Vitis Vinifera in Patients With Osteoarthritis.
Record updated
29 January 2026