Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Key facts
- Where
- Cincinnati, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 21 years old?
Source: NCT07325175, who can take part
Where in United States
- Cincinnati Children's Hospital Medical CenterCincinnati, United StatesContact: Karlee MigneaultTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Children's Hospital Medical Center, Cincinnati
- Trial code
- NCT07325175
- Record updated
- 20 October 2026
- Original description
The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are:Read full original descriptionShow less
The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are:
How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)?
Participants will:
* Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task. * Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.
Inclusion: For dystonia subjects:; Dx of dystonia (with and without DBS); willingness and ability to complete study protocols; For Typically Developing Controls:; normal developmental milestones; absence of any neuropsychiatric disorder; no significant medical condition.
Exclusion: history of epilepsy; presence of implanted medical devices (except DBS in dystonia subjects); lack of cognitive or physical ability to complete study protocol.