Exercise effects on irisin and daily life in axial spondyloarthritis
Compares two exercise styles in adults with axial spondyloarthritis, measuring irisin levels.
Plain-language title generated from the registry record
Registry title: The Effect of Exercise on Serum Irisin Levels and Clinical Parameters in Patients With Axial Spondyloarthritis.
Key facts
- Where
- Kırşehir, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18-50 with axial spondyloarthritis and high disease activity who do not exercise regularly. It compares two kinds of exercise.
- Age
- 18 to 50 years
- Sex
- Men and women
- Disease stage
- Axial spondyloarthritis (ASAS criteria) with high disease activity (ASDAS-CRP above 2.1)
- Earlier treatment
- No change in ankylosing spondylitis medicine in the last 3 months; no regular exercise in the last 3 months
Main reasons for not taking part
- Uncontrolled heart or lung disease (such as high blood pressure, COPD, heart failure)
- Other illnesses that lower the ability to exercise
- Pregnancy
- Cancer
- Recent surgery
Read by machine on 13 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT07327073, who can take part
Where in Türkiye
- Kırşehir Ahi Evran ÜniversitesiKırşehir, TürkiyeContact: Nazife Kapan Tunçer Asst. Prof.No longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Kirsehir Ahi Evran Universitesi
- Trial code
- NCT07327073
- Record updated
- 12 January 2026
- Original description
This study aimed to investigate the effects of high-intensity intermittent exercise and moderate-intensity continuous exercise on serum irisin levels, disease activity, functional status, and quality of life in patients with axial spondyloarthritis.Read full original descriptionShow less
The Effect of High-intensity Intermittent Exercise and Moderate-intensity Continuous Exercise on Serum Irisin Levels, Disease Activity, Functional Status, and Quality of Life in Patients With Axial Spondyloarthritis: a Prospective, Randomized Study
This study aimed to investigate the effects of high-intensity intermittent exercise and moderate-intensity continuous exercise on serum irisin levels, disease activity, functional status, and quality of life in patients with axial spondyloarthritis.
Inclusion: Patients diagnosed with axillary spondyloarthropathy according to ASAS diagnostic criteria,; Having a high disease severity (ASDAS-CRP above 2.1),; Being sedentary (not engaging in physical activity at least 3 days a week in the last 3 months),; Having no change in ankylosing spondylitis medical treatment in the last 3 months,; Not having any orthopedic, neurological, cardiovascular, or mental disease that would affect exercise,; Not using any assistive devices for ambulation,; Having a BMI of 25 kg/m2 or less,; Male and female patients aged 18-50 years.
Exclusion: Those who have engaged in regular exercise (aquatic exercise, land exercise, etc.) in the previous 3 months; Those with uncontrolled cardiopulmonary disease (such as hypertension, chronic obstructive pulmonary disease, heart failure),; Malignancy,; Those with a recent history of surgery,; Having comorbidities that reduce exercise capacity,; Pregnancy,.