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An Implementation Science Approach to Evaluating Self-Administered Acupressure for Knee Osteoarthritis in Older-Aged Adults in the Community

Key facts

Who runs it
The Hong Kong Polytechnic University
Where
Hong Kong1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
368 people, planned
Started
20 Dec 2025
Expected to end
30 May 2028
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Experimental Group: Self-Administered Acupressure (SAA)
  • Control Group: General Health Education
Record updated
21 September 2026

Who can take part

Age
60 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • ethnic Chinese
  • aged 60 years or above
  • able to read Chinese and comprehend Mandarin or Cantonese
  • fulfilling any 3 of the following criteria. i. morning stiffness 30 min; ii. crepitus on active joint motion; iii. bone tenderness; iv. bone enlargement; or v. no palpable joint warmth (this classification on those with age >50 years yielded 84% sensitivity, and 89% specificity for OA knee diagnosis (25))
  • having knee pain for at least 3 months (26)
  • knee pain 23 on a Likert pain scale from 1-10
  • having a smartphone (or a family member living together having a smartphone) that is compatible with WhatsApp (based on our previous studies, almost every eligible subject is used to using WhatsApp for social communication); and
  • willing to provide informed consent

Who cannot take part

  • ever had knee-replacement surgery; Further investigation or referral, either at the screening or during the study, will be made whenever necessary
  • medical diagnoses or conditions that preclude individuals from active participation (e.g., bleeding disorders, alcohol, or drug abuse)
  • knee pain related to other conditions (cancer, fracture, rheumatoid arthritis, and rheumatism) as screened according to the red flags for further investigation or referral in the NICE 2014 Guidelines for Osteoarthritis of the knee (27)
  • score < 22 in Hong Kong Montreal Cognitive Assessment (HK-MoCA) indicating cognitive impairment that may prevent the understanding of training instructions (28)
  • body mass index over 30, the obese Il criteria for Asians (29) (obese subjects will find great difficulty in performing acupressure on acupoints because physical pressure reaching the muscle is required); and

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This study aims to evaluate the implementation and effectiveness of a self-administered acupressure (SAA) program for knee osteoarthritis (OA) among older adults in Hong Kong community centers. Using a pragmatic cluster randomized controlled trial (RCT) and mixed-methods approach, the research will assess the reach, adoption, implementation, maintenance, and effectiveness of the SAA program in real-world settings, with the goal of informing scalable interventions for knee OA management.

The 2 groups in the trial

  • Self-Administered Acupressure (SAA) Intervention for Knee Osteoarthritis ManagementTreatment being tested

    A training course will be offered to subjects in this group to train them to perform self-acupressure.

    Treatment: Experimental Group: Self-Administered Acupressure (SAA)

  • General Health EducationExisting treatment, for comparison

    A booklet of general health education will be offered to the subjects in this group by the research personnel. The research staff will briefly explain the content covered by the booklet and instruct the subjects to read the booklet at home.

    Treatment: Control Group: General Health Education

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
21 September 2026