Femoral Nerve Mobilization for Patients With Knee Osteoarthritis
Key facts
- Who runs it
- Prince Sattam Bin Abdulaziz University
- Where
- Saudi Arabia1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Not yet recruiting
- People taking part
- 50 people, planned
- Started
- 20 Dec 2025
- Planned end
- 25 Feb 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- traditional physical therapy
- Femoral nerve mobilization
- Record updated
- 9 January 2026
Who can take part
- Age
- 50 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- patients aged 50 years or older, diagnosed with KO according to theAmerican College of Rheumatology's criteria with knee pain, and grade I or II on the Kellgren-Lawrence radiographic scale
Who cannot take part
- those who had undergone corticosteroid or local anesthetic infiltration in the year prior to the study or during the follow-up period
- those with a previous diagnosis of neuropathy (lumbosacral plexus) or myopathy
- individuals suffering from chronic conditions considered to be perpetuating factors (e.g., fibromyalgia)
- those with conditions causing lower extremity pain
- those with contraindications to mobilization or exercise, and those with cognitive deficits (dementia, Alzheimer's)
- individuals who had taken analgesics within 24 h before evaluations
- those using substances that could interfere with treatment
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality. There is a limited knowledge about using femoral nerve mobilization in treating patients with arthritic changes.
Read full original descriptionShow less
Objectives: This study will be designed to determine the efficacy of adding of femoral nerve mobilization on pain intensity, function, quality of life and central sensitization in patients with knee osteoarthritis Methods: Thirty patients (aged ≥50 years with KO Kellgren-Lawrence grades I-II) will be included in this study: Patients will randomly be assigned into two groups: group A will receive traditional physical therapy while group B will receive femoral nerve mobilization in addition to traditional physical therapy. Three sessions will be performed for four weeks by 3 session /week. Patients will be evaluated for pain intensity using the numerical rating scale (NRS), knee function by WOMAC scale, quality of life by 12-item Short Form Survey questionnaire (SF-12) and central sensitization by the Arabic version of central sensitization inventory (CSI).
The 2 groups in the trial
- Control groupExisting treatment, for comparison
Traditional physical therapy
Treatment: traditional physical therapy
- Neural mobilization groupTreatment being tested
traditional physical therapy plus femoral nerve mobilization
Treatment: traditional physical therapy and Femoral nerve mobilization
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effects of Femoral Nerve Mobilization on Pain Intensity, Function, Quality of Life and Central Sensitization in Patients With Knee Osteoarthritis
- Record updated
- 9 January 2026