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Measuring body composition in people with lung scarring who take anti-fibrotic medicines

Looks at body composition changes in adults with idiopathic pulmonary fibrosis or progressive pulmonary fibrosis.

Plain-language title generated from the registry record
Registry title: A Pilot Study to Assess Body Mass Composition Measurement Using BIA and Muscle Ultrasound in IPF and PPF Patients on Anti-fibrotic Medications

Key facts

Where
London, United KingdomSee the site

Where in United Kingdom

  • Royal Brompton HospitalLondon, United KingdomTaking people

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Trial details

Who runs it
Royal Brompton & Harefield NHS Foundation Trust
Trial code
NCT07332117
Record updated
12 January 2026
Original description
To assess the impact on body mass composition from anti-fibrotic medications used in fibrotic lung disease by using BIA and muscle ultrasoundRead full original descriptionShow less

A Pilot Study to Assess Body Mass Composition Measurement Using BIA and Muscle Ultrasound in IPF and PPF Patients on Anti-fibrotic Medications

To assess the impact on body mass composition from anti-fibrotic medications used in fibrotic lung disease by using BIA and muscle ultrasound

Inclusion: A diagnosis of Idiopathic pulmonary fibrosis or progressive pulmonary fibrosis; Newly commencing anti-fibrotic medication (either nintedanib or pirfenidone); Subject aged > 18 years; Able to willingly give consent.

Exclusion: Previous anti-fibrotic use; Currently on > Prednisolone 10mg daily; Heart failure; Co-morbidities currently requiring enteral feeding; Weight loss > 10% in preceding 3-6 months; Significant musculoskeletal issues that may impact muscle mass; End of life care (expected < 6 weeks left to live); Presence of implantable cardioverter defibrillator (ICD) or permanent pacemaker (PPM); Pregnancy.

ClinicalTrials.gov NCT07332117