Optic nerve ultrasound to check for brain swelling and raised pressure in intensive care
Tests optic nerve ultrasound for spotting brain swelling and inflammation in intensive care patients.
Plain-language title generated from the registry record
Registry title: Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies
Key facts
- Where
- Bucharest, RomaniaSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07332234, who can take part
Where in Romania
- "Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical DiseasesBucharest, RomaniaTaking people
- Fundeni Clinical InstituteBucharest, RomaniaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"
- Trial code
- NCT07332234
- Record updated
- 12 January 2026
- Original description
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.Read full original descriptionShow less
Utility of Optic Nerve Ultrasonography in Assessing Cerebral Inflammation and Intracranial Hypertension in Patients With Cerebral Impairment
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.
Inclusion: Patients admitted into one of the specified wards of the involved hospitals; Patients aged 18-60 years; Suspected meningitis, encephalitis, stroke or cerebral tumors.
Exclusion: Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma); Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections); Age under 18 years or over 60 years old.