Tests stool bacteria transplant in people with Alzheimer's disease
Tests a transplant of donor stool bacteria in adults with Alzheimer's disease.
Plain-language title generated from the registry record
Registry title: Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study
Key facts
- Where
- Tromsø, NorwaySee the site
- Phase
- Phase 1
Where in Norway
- University Hospital of North Norway, TromsøTromsø, NorwayTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital of North Norway
- Trial code
- NCT07332260
- Record updated
- 22 April 2026
- Original description
The goal of this study is to assess the feasibility and safety of faecal microbiota transplantation for Alzheimer's disease.Read full original descriptionShow less
Alzheimer's Disease and Faecal Microbiota Transplantation
The goal of this study is to assess the feasibility and safety of faecal microbiota transplantation for Alzheimer's disease.
Inclusion: Alzheimer's dementia mild to moderate stage; Presence of Alzheimer pathology core 1 biomarkers as defined by National Institute on Aging-Alzheimer's Association (NIA-AA) criteria (2024); Capable of giving informed consent.
Exclusion: Receiving biological/antibody treatment; History of seizure disorder; History of brain tumour or intracranial bleed; Major psychiatric disorder such as schizophrenia, bipolar disorder, or major depressive disorder; Decompensated heart disease; Malignancy; Inflammatory bowel disease; Contraindications for colonoscopy examination; Contraindications for Magnetic Resonance Imaging (MRI); Life expectancy < 1 year; Clinical frailty scale 7 or more; Alcohol or substance abuse; Current use of anticoagulant treatment (dual acting oral anticoagulant or warfarin); Pregnant or planning pregnancy; Colonic adenomas over 1 cm, tumours or signs of active colitis on colonoscopy; Status after colectomy or hemicolectomy; Immunocompromised individual.