Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing
Key facts
- Where
- Wenzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 15 years old?
Source: NCT07332780, who can take part
Where in China
- The Second Affiliated Hospital of Wenzhou Medical UniversityWenzhou, ChinaContact: Xiangyang Wang, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Second Affiliated Hospital of Wenzhou Medical University
- Trial code
- NCT07332780
- Record updated
- 15 May 2026
- Original description
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in preventing the de novo development of scoliosis in children with SDB.Read full original descriptionShow less
A Randomized Controlled Study of Adenotonsillectomy on Spinal Curve Magnitude in Children With Mild Sleep-Disordered Breathing
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in preventing the de novo development of scoliosis in children with SDB.
Inclusion: Age between 6 and 15 years; Diagnosed with mild SDB, defined as: Obstructive Apnea-Hypopnea Index (OAHI) ≤5 events/hour on a laboratory-based PSG performed within the past 6 months, AND parental report of habitual obstructive breathing symptoms (e.g., snoring, mouth-breathing, witnessed apneas) occurring >3 nights per week on average; Tonsillar hypertrophy grade ≥2 (on a scale of 0-4) and deemed an appropriate candidate for AT upon ENT evaluation (i.e., no absolute contraindications such as submucous cleft palate); Has undergone radiographic screening for idiopathic scoliosis at the first clinic visit; Skeletally immature (Risser sign 0-3) with spinal Cobb angle < 40 degrees; Informed consent/assent provided by the participant and guardian.
Exclusion: Previous tonsillectomy or adenoidectomy; Severe OSA (OAHI >10 or as per clinician judgment) or significant hypoxemia requiring immediate CPAP therapy; Severe chronic conditions that could confound outcomes, including but not limited to:; Known syndromic, neuromuscular, or congenital musculoskeletal causes of scoliosis; History of spine surgery or significant spinal injury; Spinal tumor; Leg length discrepancy >20 mm; Severe cardiopulmonary disease (e.g., cystic fibrosis, congenital heart disease); Significant cardiac arrhythmia noted on PSG; Bleeding disorders, Sickle Cell Disease; Uncontrolled diabetes, narcolepsy, or asthma; Known genetic, craniofacial, neurological, or psychiatric conditions likely to affect the airway or study participation; Severe obesity (BMI z-score ≥ 3); Unwillingness or inability to comply with study procedures; Plans to relocate outside the study area within 24 months; Recurrent tonsillitis meeting guideline criteria for immediate AT.