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Studies platelet changes in patients on ECMO heart and lung support

Observes how platelet populations change in adults with heart or lung failure on ECMO.

Plain-language title generated from the registry record
Registry title: Study of Platelet Population Changes Under Circulatory Support With ECMO

Key facts

Where
Strasbourg, FranceSee the site

Where in France

  • Service d'anesthésie-réanimation - CHU de Strasbourg - FranceStrasbourg, FranceTaking people

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Trial details

Who runs it
University Hospital, Strasbourg, France
Trial code
NCT07334457
Record updated
12 January 2026
Original description
Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.Read full original descriptionShow less

Study of Platelet Population Changes Under Circulatory Support With ECMO

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Inclusion: Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital; Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.

Exclusion: Subject who has expressed their opposition to participating in the study; Subject under legal protection; Subject under guardianship or curatorship.

ClinicalTrials.gov NCT07334457