Testing brain and spinal cord stimulation during tasks after stroke or spinal injury
Tests combined non-invasive brain and spinal stimulation in adults with stroke or spinal injury.
Plain-language title generated from the registry record
Registry title: Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
Key facts
- Where
- Bordeaux and Bruges, FranceSee the 2 sites
- Phase
- Phase 2
Where in France
- Service de Médecine Physique & Réadaptation - CHU BordeauxBordeaux, FranceTaking people
- Centre de la Tour de GassiesBruges, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre National de la Recherche Scientifique, France
- Trial code
- NCT07334977
- Record updated
- 12 January 2026
- Original description
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.Read full original descriptionShow less
Synergistic Potential of Non-invasive Brain and Spinal Cord Stimulation for Improving Sensorimotor and Cognitive Functions After Neurological Injury
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.
Inclusion: CONTROL GROUP:; Over 18 years of age; Participant who has signed an informed consent form; Participant who is affiliated with and covered by the social security system; POST-STROKE GROUP:; Over 18 years of age; Who sustained a stroke more than 3 weeks ago; Considered medically stable by the medical investigator; Who has signed an informed consent form; Affiliated with and covered by the social security system; SCI GROUP:; Over 18 years of age; Considered to have a complete or incomplete spinal cord injury (i.e., with a score on the Spinal Injury Association (ASIA) Impairment Scale (AIS) score from A to D); Considered medically stable by the investigating physician; Presenting with quadriplegia due to cervical injury; Who has signed an informed consent form; Affiliated with and covered by the social security system.
Exclusion: Suffering from a chronic condition; History of epilepsy or seizures; Presence of a contraindication to the use of magnetic/electrical stimulation or MRI, including: cardiac pacemaker; implanted hearing aid; intraocular foreign body, shrapnel, or bullets; metal worker; pacemaker or neurostimulator; claustrophobia; Presence of implanted medical devices (cardiac valve, endovascular devices, ventricular shunt valve, surgical clips, metallic sutures, staples, stent, osteosynthesis or arthrodesis hardware) not classified as "MR Conditional" according to ASTM F2503; Skin problems or open wounds; Individuals who are legally incompetent, under judicial protection, guardianship, or trusteeship; Pregnant and/or breastfeeding women; Individuals who refuse to be informed of any abnormalities that may be detected by MRI.