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Taking people in United StatesNo phase

Neuroimaging of Adolescent Cannabis Use Treatment

Key facts

Who runs it
Indiana University
Where
Indianapolis, United StatesSee the site
Trial code
Status
Recruiting
People taking part
80 people, planned
Started
15 Jun 2026
Expected to end
1 May 2030
Type of study
Interventional
Treatments tested
  • Contingency Management
  • Elastic Net Regression
Record updated
22 June 2026

Who can take part

Age
14 years to 17 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • 14-17 year old youth
  • Guardian 18 years or older
  • Youth is MRI-eligible: No metal implants, prosthetics, orthodontic devices, transdermal medication patches, piercings and/or hair or eyelash extensions that cannot easily be removed, metallic ink tattoos on the neck or face, or claustrophobia, and are not pregnant
  • Youth must endorse having used cannabis at least once per week over the past month OR youth must have been diagnosed with cannabis use disorder within the past three months

Who cannot take part

  • Youth has a history of Fetal Alcohol Spectrum Disorder, intellectual disorders, pervasive development disorder or autism spectrum disorder, psychotic disorders, history of neurological problems (epilepsy, traumatic brain injury, brain tumor, cerebrovascular disease) by parent/guardian report
  • Youth who is currently undergoing contingency management treatment for cannabis use disorder
  • Youth or caretaker who is monolingual non-English speaker
  • Youth who is currently experiencing active psychosis symptoms or suicidal/homicidal ideation or who has been hospitalized within the past 6 months for psychosis or suicidality/homicidality

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 14 and 17 years old?

Where in United States

  • Indiana University School of MedicineIndianapolis, United StatesContact: Joseph Aloi, MD, PhDTaking people

About the trial

What the trial wants to find out

This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use. Teens ages 14-17 will complete a brain scan and then take part in 10 weekly virtual sessions where they report cannabis use and complete drug tests at home. Participants can earn prizes for staying cannabis-free.

The group in the trial

  • Contingency Management and Elastic Net RegressionOther group

    All participants will receive Contingency Management treatment for Cannabis Use. An elastic net regression model will be applied to the neuroimaging data for all participants to estimate scores on the CUDIT.

    Treatment: Contingency Management and Elastic Net Regression

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Neuroimaging of Instrumental Learning Networks in Adolescent Cannabis Use Treatment
Fit questions
Built from NCT07340554, who can take part
Record updated
22 June 2026
Neuroimaging of Adolescent Cannabis Use Treatment (NCT07340554) – Frontlight Research