How Heat Affects Blood Sugar During Exercise in Adults With Type 1 Diabetes
Compares blood sugar during moderate exercise in heat and mild temperature in type 1 diabetes.
Plain-language title generated from the registry record
Registry title: Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D
Key facts
- Where
- Liverpool, United KingdomSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07341243, who can take part
Where in United Kingdom
- Liverpool John Moores UniversityLiverpool, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Liverpool John Moores University
- Trial code
- NCT07341243
- Record updated
- 14 January 2026
- Original description
A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise. Participants will complete two experimental conditions during two separate laboratory visits, with the order of conditions randomised. One condition will be a temperate condition of 20°C with 50% relative humidity (Temperate), the other will be 40°C with 50% relative humidity (Heat). Visits will be identical, including time of day, except for the condition. Visits will be separated by 24h. Testing will take place in the laboratories of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University.Read full original descriptionShow less
The Effect of Acute Heat Exposure on Glucose Use During Moderate-intensity Exercise in People With Type 1 Diabetes
A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise. Participants will complete two experimental conditions during two separate laboratory visits, with the order of conditions randomised. One condition will be a temperate condition of 20°C with 50% relative humidity (Temperate), the other will be 40°C with 50% relative humidity (Heat). Visits will be identical, including time of day, except for the condition. Visits will be separated by 24h. Testing will take place in the laboratories of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University.
Inclusion: T1D diagnosis more than 1 years ago (to ensure participants are out of the honeymoon period); Using insulin therapy with multiple daily injections (MDI), insulin pump (pump), or hybrid closed-loop (HCL); o If using a HCL system have experience of using a pre-programmed basal rate in manual mode during exercise; Aged 18-65 years; Regularly engaged in endurance exercise (training at least twice per week for ≥30 minutes per session).
Exclusion: <6 months postpartum or stopped breastfeeding <1 month before recruitment; Existing cerebrovascular or cardiovascular disease; History of severe hypoglycaemia requiring third party assistance within the last 3 months; Obstructive gastrointestinal disease; History of gastrointestinal surgery; Significant history of hyperglycaemia (HbA1c >85 mmol/mol); Pregnancy; Body weight <36.5kg; Difficulty swallowing tablets; Appointment for an MRI test that cannot be rescheduled; Have an implanted medical device.