Compares clot removal and medicine alone for large basilar artery strokes
Looks back at adults with a large stroke from a blocked basilar artery.
Plain-language title generated from the registry record
Registry title: Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct
Key facts
- Where
- Beijing, ChinaSee the site
Where in China
- Xuanwu HospitalBeijing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Xuanwu Hospital, Beijing
- Trial code
- NCT07345702
- Record updated
- 30 July 2026
- Original description
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.Read full original descriptionShow less
Endovascular Versus Medical Therapy for Acute Large-Core Basilar Artery Occlusion: A Multicenter Retrospective Registry Study (BAOCHE-LC)
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.
Inclusion: Age ≥18 years, men or women; Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA/MRA/DSA; Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days; Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.
Exclusion: CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed); Any other condition judged by investigators to substantially affect analysis or interpretation; Subjects with occlusions in both anterior and posterior circulation; Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset/last known well time, or missing major treatment information including whether EVT was performed); Baseline NIHSS score <6; Woman of childbearing potential who is known to be pregnant or lactating or who has a positive pregnancy test on admission; Missing follow-up outcomes at 90 days.