Finger pulse imaging to assess aortic valve disease in adults
Tests whether finger pulse imaging can assess aortic valve disease in adults.
Key facts
- Who runs it
- Anhui Provincial Cancer Hospital
- Where
- China1 site in 1 countryChoose a country to see its sites
- Trial code
- Registry title
- Noninvasive Real-Time Arterial Waveform Monitoring for Cardiovascular Disease Assessment
- Status
- Recruiting
- People taking part
- 15 people, planned
- Started
- 26 Dec 2025
- Planned end
- Feb 2026
- Type of study
- Observational, 3 groups
- Record updated
- 20 January 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with aortic regurgitation (a leaky aortic heart valve) or aortic stenosis (a narrowed aortic valve), and healthy adults. A device records the pulse in the finger without needles or cuts.
- Age
- 18 to 80 years
- Sex
- All sexes
- Disease stage
- Patients need a doctor's diagnosis of aortic regurgitation or aortic stenosis. Healthy volunteers must have no history of heart or blood vessel disease.
- Earlier treatment
- People who had heart surgery or a heart procedure in the last 6 months cannot join.
Main reasons for not taking part
- Heart surgery or a heart procedure in the last 6 months
- Hand problems that limit finger movement, such as arthritis
- Being pregnant or breastfeeding
- Taking part in other studies that affect the pulse wave
- Not able to understand or follow the study steps
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Age 18-80 years
- Able to provide informed consent
- For AR group: clinically diagnosed aortic regurgitation
- For AS group: clinically diagnosed aortic stenosis
- For healthy controls: no history of cardiovascular disease
- Able to undergo finger arterial waveform measurement
Who cannot take part
- History of recent cardiac surgery or intervention (<6 months)
- Hand disorders affecting finger mobility (e.g., arthritis)
- Pregnant or breastfeeding women
- Participation in other studies affecting arterial waveform
- Unable to understand or comply with study procedures
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The goal of this observational study is to learn whether noninvasive real-time arterial waveform monitoring can be used to assess cardiovascular diseases in adults. The main question it aims to answer is:
Read full original descriptionShow less
Can photoacoustic imaging accurately capture arterial waveforms from patients' fingers? Can features extracted from the arterial waveforms reflect the type and severity of cardiovascular diseases? Participants will be asked to place their fingers into the imaging device, where their finger arterial pulse information will be noninvasively recorded.
The 3 groups in the trial
- Healthy Subjects
Healthy adult volunteers with no known cardiovascular disease will undergo noninvasive arterial waveform acquisition using the photoacoustic imaging device. No intervention is applied; data collection provides baseline waveform features for comparison with AR and AS patients.
- Aortic Regurgitation (AR) Patients
Participants diagnosed with aortic regurgitation (AR) will undergo noninvasive arterial waveform acquisition using a photoacoustic imaging device. No intervention is applied; data collection focuses on capturing finger arterial pulse waveforms to assess features associated with AR.
- Aortic Stenosis (AS) Patients
Participants diagnosed with aortic stenosis (AS) will undergo noninvasive arterial waveform acquisition using the same photoacoustic imaging device. No intervention is applied; data collection focuses on capturing finger arterial pulse waveforms to assess features associated with AS.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Study on Noninvasive Real-Time Arterial Pressure Waveform Analysis for the Detection and Evaluation of Cardiovascular Diseases
- Plain-language title
- Finger pulse imaging to assess aortic valve disease in adultsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Fit questions
- Built from NCT07350629, who can take part
- Record updated
- 20 January 2026