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NCT07351786Recruiting

Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy

Source: ClinicalTrials.gov · Last updated 20 Jan 2026

Brief summary (registry, in English)

This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR). The study hypothesizes that these drugs have protective effects in diabetic retinopathy by delaying its incidence compared to older agents (including metformin) only. Early intervention is critical, as treatment options for advanced stages of DR are limited in terms of their ability to restore impaired vision and their high associated costs. By focusing on delaying the occurrence of diabetic retinopathy, the investigators aim to reduce the burden of DR and improve the quality of life for diabetic patients.

Status (registry)
Recruiting
Study type
Observational
Enrollment
70 (estimated)
First submitted
18 Dec 2025
Start date
1 Aug 2025
Primary completion date
1 Aug 2026
Lead sponsor
Sara A Belal
NCT number
NCT07351786

What you commit to

  • Study type: Observational
  • Planned participants: 70
  • From 1 Aug 2025 to the primary completion date, 1 Aug 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Gestational Diabetes
  • Type 1 Diabetes

Other

  • Severe non-proliferative diabetic retinopathy (NPDR) at baseline
  • Proliferative diabetic retinopathy (PDR) at baseline
  • Pregnant and breastfeeding women

Who the study is looking for

  • Diagnosed with Type 2 Diabetes for \>5 years
  • Using Diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors) for a period of 2-3 years

Age in the registry: 25 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Alexandria University Main Hospitals - Diabetes clinics/ Ophthalmology clinics
Coordinator of this site? Confirm its status
AlexandriaEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.