Ultrasound imaging inside vessels during leg artery treatment for peripheral artery disease
Tests ultrasound imaging inside vessels when opening blocked leg arteries in peripheral artery disease.
Key facts
- Who runs it
- Baylor Research Institute
- Where
- Dallas, Fort Worth, McKinney, Plano, Temple, and Waxahachie, United StatesSee the 6 sites
- Trial code
- Registry title
- Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries
- Status
- Recruiting
- People taking part
- 350 people, planned
- Started
- 12 Dec 2025
- Expected to end
- Jul 2028
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Intravascular Ultrasound (IVUS)
- Angiographic-guided Intervention
- Record updated
- 9 July 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with leg artery disease that causes symptoms and who are having a minimally invasive procedure to open a narrowed leg artery.
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Peripheral artery disease of the legs with symptoms, Rutherford Class 2-5. An X-ray of the blood vessels (angiogram) must show more than 50% narrowing. The treated narrowing is in the iliac, femoropopliteal, profunda or below-the-knee arteries above the ankle.
- Earlier treatment
- People cannot join if the treated narrowing was treated with a procedure within 6 months.
Main reasons for not taking part
- A procedure at the treated narrowing within 6 months
- Treated narrowing is in the abdominal aorta
- Treated narrowing is in below-the-knee arteries below the ankle
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Age ≥18 years
- Symptomatic LE PAD - Rutherford Class 2-5
- Angiographic evidence of >50% stenosis
- Undergoing LE peripheral artery intervention
- Target lesion is iliac, femoropopliteal, profunda or supramalleolar below-the-knee arteries (target lesions extending into the abdominal aorta and inframalleolar BTK may be included)
Who cannot take part
- Prior intervention at the target lesion within 6 months
- Target lesion is abdominal aorta or inframalleolar BTK arteries
Where in United States
- Baylor Scott & White The Heart Hospital - DallasDallas, United StatesContact: Sarah HaleTaking people
- Baylor Scott & White The Heart Hospital - Fort WorthFort Worth, United StatesContact: Theresa CheyneNot yet recruiting
- Baylor Scott & White The Heart Hospital - MckinneyMcKinney, United StatesContact: Denise EspinozaTaking people
- The Heart Hospital Baylor PlanoPlano, United StatesContact: Osniel Gonzalez Ramos, BSTaking people
- Baylor Scott & White Medical Center - TempleTemple, United StatesContact: Margarite GrableNot yet recruiting
- Baylor Scott & White The Heart Hospital - WaxahachieWaxahachie, United StatesContact: Sarah HaleTaking people
About the trial
What the trial wants to find out
This study will test whether using ultrasound imaging within blood vessels during minimally invasive treatment of leg arteries in patients with peripheral artery disease leads to better clinical outcomes.
The 2 groups in the trial
- Intravascular Ultrasound (IVUS)Existing treatment, for comparison
Intravascular Ultrasound (IVUS) is used during the treatment of the target lesion.
- Non-Intravascular Ultrasound (IVUS)Existing treatment, for comparison
Intravascular Ultrasound (IVUS) is not used in the treatment of the target lesion.
Treatment: Angiographic-guided Intervention
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries
- Plain-language title
- Ultrasound imaging inside vessels during leg artery treatment for peripheral artery diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 9 July 2026