Focused ultrasound for epilepsy that does not respond to medicines
Tests low-intensity focused ultrasound in adults with hard-to-treat epilepsy who have implanted electrodes.
Plain-language title generated from the registry record
Registry title: Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy
Key facts
- Where
- Roanoke, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT07353918, who can take part
Where in United States
- Fralin Biomedical Research Institute at VTCRoanoke, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Carilion Clinic
- Trial code
- NCT07353918
- Record updated
- 21 January 2026
- Original description
This study is an invite only study looking at the effects of Low-Intensity Focused Ultrasound (LIFU) on epilepsy patients with implanted electrodes under the care of Dr. Shah.Read full original descriptionShow less
Neuromodulation Using Low-intensity Focused Ultrasound for Potential Treatment for Medically Refractory Temporal Lobe Epilepsy
This study is an invite only study looking at the effects of Low-Intensity Focused Ultrasound (LIFU) on epilepsy patients with implanted electrodes under the care of Dr. Shah.
Inclusion: Diagnosis of medically refractory focal epilepsy of mesial temporal onset; RNS system implantation in the hippocampus; Prior MRI and CT of the head; Able to consent for themselves; Internet access.
Exclusion: TBI (ongoing, or in the prior 6 months); Progressive diseases - such as autoimmune epilepsies or diagnosis of a progressive neurological disorder; History of suicidal ideation or attempts in the last 6 months; Currently pregnant or breastfeeding; Status epilepticus within one year of study start.