Tests iStent device with cataract surgery for glaucoma eye pressure
Tests an iStent device during cataract surgery in adults with glaucoma.
Plain-language title generated from the registry record
Registry title: Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma
Key facts
- Where
- Hangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07354009, who can take part
Where in China
- Eye Center, the 2nd Affiliated Hospital, Medical College of Zhejiang UniversityHangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- Trial code
- NCT07354009
- Record updated
- 21 January 2026
- Original description
To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.Read full original descriptionShow less
Evaluation of the Efficacy and Safety of iStent in Reducing Intraocular Pressure in Adult Patients With Open-angle Glaucoma and Cataract
To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.
Inclusion: Gender is not limited. Applicants must be 18 years old or above; Study patients whose eyes were diagnosed with open-angle glaucoma; The study eye was diagnosed with cataract and met the conditions for phacoemulsification, with the best corrected visual acuity ≤0.7(patients with the best corrected visual acuity >0.7 who were determined by the researcher to need cataract surgery could be enrolled); Angular endoscopy confirmed that the opening Angle of the study eye was normal (defined as Shaffer grade ≥3, and there was no peripheral anterior iris adhesion, polycythemia or other abnormal conditions that might affect the correct placement of the stent); The patient is capable and willing to provide written informed consent and participate in the regular postoperative follow-up as required.
Exclusion: Suffering from severe diabetic retinopathy, retinal detachment, central retinal vein or artery occlusion, retinal chromosomal degeneration, macular degeneration, macular edema, and determined by researchers to potentially affect surgical safety; Having clinically significant corneal dystrophy, active inflammation or having undergone surgery that may interfere with the reliability of intraocular pressure measurement; Patients with traumatic, malignant uveitis, neovascular or glaucoma related to vascular diseases; Patients with retrobulbar tumors, thyroid eye disease, cavernous sinus fistula, Sturge-Weber syndrome or any other disease that may cause elevated venous pressure in the outer sclera; Suffering from eye or systemic diseases that affect surgical safety or subsequent examinations; Failure to follow the doctor's advice; Pregnant women, lactating women, women of childbearing age who plan to get pregnant during the research period or are unable to take effective contraceptive measures; Patients with angle-closure, pigmentary or pseudo-exfoliative glaucoma; Patients with identifiable congenital abnormalities of the anterior chamber Angle; Other circumstances where the researcher determines that the patient is not suitable for inclusion.