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Not yet taking people in TaiwanPhase 4

Tests lidocaine to ease coughing and diaphragm movement during heart ablation

Tests intravenous lidocaine against saline in adults having pulsed field ablation for atrial fibrillation.

Plain-language title generated from the registry record
Registry title: Workflow Optimization During Pulse Field Ablation for Atrial Fibrillation

Key facts

Where
Taipei, TaiwanSee the site
Phase
Phase 4

Where in Taiwan

  • National Taiwan University HospitaTaipei, TaiwanNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
National Taiwan University Hospital
Trial code
NCT07354217
Record updated
20 April 2026
Original description
To evaluate the efficacy and safety of intravenous lidocaine in reducing diaphragmatic contraction and suppressing the cough reflex during pulsed field ablation procedures.Read full original descriptionShow less

Workflow Optimization During Pulse Field Ablation for Atrial Fibrillation

To evaluate the efficacy and safety of intravenous lidocaine in reducing diaphragmatic contraction and suppressing the cough reflex during pulsed field ablation procedures.

Inclusion: Patients with paroxysmal or persistent AF and are scheduled to undergo PVI; Patients who can understand the study aims and protocol and are willing to follow the protocol for one year.

Exclusion: Known allergy to study drug lidocaine; Underlying significant pulmonary disease, such as asthma or COPD needing long term maintenance therapy or documented interstitial lung disease; Informed consent could not be obtained; Presence of thrombus in the LA or LA appendage.

ClinicalTrials.gov NCT07354217