Comparing two pacing settings in new implanted defibrillators for fast heart rhythms
Compares burst and ramp pacing settings in people receiving a new defibrillator.
Plain-language title generated from the registry record
Registry title: Optimal Settings for Anti Tachycardia Pacing (ATP) on ICD
Key facts
- Where
- Copenhagen, DenmarkSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults getting a new implantable cardioverter defibrillator (ICD) to prevent dangerous fast heart rhythms. It compares two ways of setting the pacing treatment.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- People with heart disease who are getting a new ICD to prevent a dangerous heart rhythm, either before or after one has happened.
Main reasons for not taking part
- People can choose to opt out of the study
Read by machine on 13 November 2026.
Where in Denmark
- The Heart Center, RigshospitaletCopenhagen, DenmarkContact: Bo G Winkel, MD, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Copenhagen University Hospital, Rigshospitalet
- Trial code
- NCT07354347
- Record updated
- 4 September 2026
- Original description
This is a pragmatic, two-group, cluster randomized trial designed to compare strategies for the Anti Tachycardia Pacing (ATP)-setting in the ventricular tachyarrhythmias (VT) zone when implanting a new implantable cardioverter defibrillator (ICD) in patients with heart disease in hospitals in Denmark.Read full original descriptionShow less
Optimal ATP Settings in the VT Zone for New Implantable Cardioverter Defibrillator (ICD) Implantation (DAN-ATP)
This is a pragmatic, two-group, cluster randomized trial designed to compare strategies for the Anti Tachycardia Pacing (ATP)-setting in the ventricular tachyarrhythmias (VT) zone when implanting a new implantable cardioverter defibrillator (ICD) in patients with heart disease in hospitals in Denmark.
The strategies are: "Burst" or "Ramp" after 1. ATP (which is always burst) in VT zone. VT zone is defined between 180-249 (up to 269 in special cases) heartbeats per minute.
The ICD will give either:
Burst: The ICD is programmed to give ATP with 4 bursts. Or Ramp: The ICD is programmed to give ATP with 1 burst and 3 ramps.
The participating hospitals will be assigned to one of two intervention strategies for periods of 4-months. The given intervention will follow the patient/ICD throughout the life time of the ICD, but with the possibility to reprogram at any time (intention to treat).
It is calculated that the study needs a total of 398 events (second to fourth ATP), which is estimated to require 3980 implanted ICDs. The participants will be followed until the end of the ICD life, which is estimated to be around 10 years.
Inclusion: ICD implantation for primary or secondary prophylactic indication.
Exclusion: None; Patients can actively opt out of participation in the study.