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Adding Weight Training to Cycling Exercise in Women With Coronary Artery Disease

Tests weight training added to cycling intervals in women with coronary artery disease.

Plain-language title generated from the registry record
Registry title: Resistance Training Added to Aerobic Interval Training to Improve Aerobic Capacity and Muscle Mass in Women With Coronary Artery Disease

Key facts

Where
Ljubljana, SloveniaSee the site

Where in Slovenia

  • University Medical Centre Ljubljana (Department of Vascular Diseases, Division of Internal Medicine)Ljubljana, SloveniaTaking people

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Trial details

Who runs it
University Medical Centre Ljubljana
Trial code
NCT07354399
Record updated
21 January 2026
Original description
The goal of this clinical trial is to find out whether partly replacing aerobic interval training (AIT) with resistance training (RT) leads to greater improvements in physical fitness and muscle mass in women with coronary artery disease (CAD) during cardiac rehabilitation.Read full original descriptionShow less

Resistance Training Among Women With Coronary Artery Disease

The goal of this clinical trial is to find out whether partly replacing aerobic interval training (AIT) with resistance training (RT) leads to greater improvements in physical fitness and muscle mass in women with coronary artery disease (CAD) during cardiac rehabilitation.

The main questions this study aims to answer are:

* Does combining RT (squats and pulling exercises with weights) with a reduced amount of AIT (cycling) improve aerobic fitness in the same way as AIT alone? * Does the combined training lead to greater improvements in muscle mass compared with AIT alone? * Does slow-speed RT (slower lowering phase) result in lower heart rate and blood pressure during exercise compared with normal-speed RT?

Researchers will compare three exercise programs:

* AIT only (control group), * AIT combined with normal-speed RT (1-second lifting, 2-second lowering), * AIT combined with slow-speed RT (1-second lifting, 5-second lowering).

Participants will take part in a 12-week cardiac rehabilitation program and will train three times per week.

At the start and end of the program, participants will complete a cycling fitness test, body composition assessment, blood sampling, two strength tests, and quality-of-life questionnaire.

Inclusion: documented CAD,; stable clinical status (at least 1 month since myocardial infarction and/or elective percutaneous coronary intervention, at least 3 months since cardiac surgery).

Exclusion: based on the American Heart Association guidelines for resistance training in patients with CAD,; pregnancy.

ClinicalTrials.gov NCT07354399