Studies mouth and saliva markers in adults with stroke
Compares saliva and mouth bacteria markers in adults with stroke and healthy adults.
Plain-language title generated from the registry record
Registry title: Oral and Salivary Biomarkers Associated With Stroke
Key facts
- Where
- Constantine, AlgeriaSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07357155, who can take part
Where in Algeria
- Private Dental Clinic, ConstantineConstantine, AlgeriaNo longer taking part
- University Hospital Center (CHU) of ConstantineConstantine, AlgeriaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Center (CHU) of Constantine, Algeria
- Trial code
- NCT07357155
- Record updated
- 8 October 2026
- Original description
This observational study aims to investigate associations between oral and salivary biomarkers and stroke. Adults with stroke and healthy controls will undergo clinical oral assessment and unstimulated saliva collection. Salivary inflammatory biomarkers and oral bacterial profiles will be analyzed, including detection of Streptococcus mutans and the cnm gene by PCR/qPCR. The study will explore associations between these biomarkers and stroke status.Read full original descriptionShow less
An Observational Study of Oral and Salivary Biomarkers Associated With Stroke
This observational study aims to investigate associations between oral and salivary biomarkers and stroke. Adults with stroke and healthy controls will undergo clinical oral assessment and unstimulated saliva collection. Salivary inflammatory biomarkers and oral bacterial profiles will be analyzed, including detection of Streptococcus mutans and the cnm gene by PCR/qPCR. The study will explore associations between these biomarkers and stroke status.
Inclusion: Adults aged 18 to 90 years; Patients diagnosed with stroke (ischemic or hemorrhagic) confirmed by clinical and imaging criteria for the stroke group; Healthy volunteers without a history of stroke or cerebrovascular disease for the control group; Ability to provide written informed consent.
Exclusion: Recent major surgery or trauma within the last 3 months; inflammatory disease at the time of sampling; Chronic autoimmune or malignant disease; Pregnancy or breastfeeding; Inability or refusal to provide saliva samples.