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Handedness and Arm Recovery After Stroke

Observes whether handedness is linked to arm recovery in adults after a recent stroke.

Plain-language title generated from the registry record
Registry title: Influence of Handedness on Upper Limb Recovery

Key facts

Where
Orléans, FranceSee the site

Where in France

  • CHU OrléansOrléans, FranceTaking people

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Trial details

Who runs it
Centre Hospitalier Régional d'Orléans
Trial code
NCT07357181
Record updated
8 June 2026
Original description
This prospective, single-center observational study evaluates whether handedness is associated with upper-limb motor recovery after a recent unilateral stroke. Adults admitted to the stroke unit with a confirmed unilateral stroke within 5 days are included if they do not object to participation. Upper-limb impairment is assessed early after stroke and at 6 months using standardized clinical scales. Handedness is determined by self-report, and the Edinburgh Handedness Inventory is administered when feasible. The main hypothesis is that left-handed participants may show better upper-limb motor recovery at 6 months than right-handed participants, potentially due to differences in brain motor network lateralization.Read full original descriptionShow less

Impact of Manual Preference on Motor Deficits After Stroke

This prospective, single-center observational study evaluates whether handedness is associated with upper-limb motor recovery after a recent unilateral stroke. Adults admitted to the stroke unit with a confirmed unilateral stroke within 5 days are included if they do not object to participation. Upper-limb impairment is assessed early after stroke and at 6 months using standardized clinical scales. Handedness is determined by self-report, and the Edinburgh Handedness Inventory is administered when feasible. The main hypothesis is that left-handed participants may show better upper-limb motor recovery at 6 months than right-handed participants, potentially due to differences in brain motor network lateralization.

Inclusion: Confirmed unilateral recent stroke (less than 5 days); Age 18 years and older; Participant or proxy does not object to participation.

Exclusion: Prior stroke with residual motor sequelae; Pre-stroke upper-limb deficit; Follow-up at 6 months not planned at Orléans; Protected adult (guardianship/curatorship), person under legal protection, or deprived of liberty; Pregnant or breastfeeding woman.

ClinicalTrials.gov NCT07357181