Studies how the eyes, brain and kidneys interact in chronic kidney disease
Observes brain, kidney and eye scans and thinking tests in adults with chronic kidney disease.
Plain-language title generated from the registry record
Registry title: Eye-Brain-Kidney in CKD
Key facts
- Where
- Beijing, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07358572, who can take part
Where in China
- Beijing Friendship Hospital, Capital Medical UniversityBeijing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Beijing Friendship Hospital
- Trial code
- NCT07358572
- Record updated
- 27 January 2026
- Original description
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is:Read full original descriptionShow less
A Study on the Eye-Brain-Kidney Interaction Mechanisms in Chronic Kidney Disease Based on Multimodal Magnetic Resonance Imaging
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is:
Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.
Inclusion: Aged 18-70 years; Patients clinically diagnosed with CKD stages 1-5; No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan.
Exclusion: Patients with recent or prior cerebral hemorrhage or cerebral infarction; History of epileptic seizures or psychiatric disorders; Presence of other central nervous system diseases (e.g., tumor, trauma); Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction; Any systemic or other diseases deemed unsuitable for clinical trial participation; Patients with claustrophobia; Pregnant or lactating patients.