NCT07359690Recruiting
Multimodal Analysis of Endomyocardial Biopsies
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy. The main aim is: -Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course. Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 216 (estimated)
- First submitted
- 16 Dec 2025
- Start date
- 27 Oct 2025
- Primary completion date
- 30 Sept 2028
- Lead sponsor
- University Hospital, Essen
- Diseases
- Amyloidosis, Hypertrophic cardiomyopathy
- NCT number
- NCT07359690
What you commit to
- Study type: Observational
- Planned participants: 216
- From 27 Oct 2025 to the primary completion date, 30 Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients without a clinical indication for endomyocardial biopsy (EMB).
- Pregnant individuals.
- Patients incapable of providing informed consent.
- Women of childbearing potential who are not using adequate contraception.
Who the study is looking for
- Patients aged \>18 years with a clinical indication for endomyocardial biopsy.
- Patients capable of providing informed consent who have signed the consent form for participation in the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany Coordinator of this site? Confirm its status | Essen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.