Compares exercise timing during and before dialysis sessions
Tests exercise given during or before dialysis in adults with kidney failure.
Plain-language title generated from the registry record
Registry title: A Comparative Study of Intradialytic vs. Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial
Key facts
- Where
- Hawalli, KuwaitSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with end-stage kidney disease who have been on hemodialysis for at least 3 months. It compares exercise during dialysis with exercise before dialysis.
- Age
- 21 to 65 years
- Sex
- All sexes can join.
- Disease stage
- End-stage renal disease, on maintenance hemodialysis for at least 3 months.
- Earlier treatment
- Must not have joined another structured exercise program in the last 3 months.
Main reasons for not taking part
- Uncontrolled high blood pressure, recent heart attack or unstable angina
- Severe bone, muscle, nerve or heart and blood vessel disorders that limit physical activity
- Active infection, fever or open wounds
- Hospital stay within the past month
- Another structured exercise program in the last 3 months
This trial only enrols participants on dialysis. The registry sentence this rests on: Undergoing maintenance hemodialysis for at least 3 months.
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 65 years old?
Source: NCT07361146, who can take part
Where in Kuwait
- Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis CenterHawalli, KuwaitTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mohammad Arian
- Trial code
- NCT07361146
- Record updated
- 22 January 2026
- Original description
This randomized controlled trial aims to compare the effectiveness of two different timings of physical therapy for individuals undergoing hemodialysis: intradialytic (during dialysis) and pre-dialysis (before dialysis). The study seeks to determine which approach provides better improvements in physical function, quality of life, and biochemical outcomes such as hemoglobin and electrolyte levels.Read full original descriptionShow less
A Comparative Study of Intradialytic Versus Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial
This randomized controlled trial aims to compare the effectiveness of two different timings of physical therapy for individuals undergoing hemodialysis: intradialytic (during dialysis) and pre-dialysis (before dialysis). The study seeks to determine which approach provides better improvements in physical function, quality of life, and biochemical outcomes such as hemoglobin and electrolyte levels.
A total of 72 adult participants with end-stage renal disease (ESRD) receiving hemodialysis will be randomly assigned to one of two groups. Both groups will receive standardized educational sessions on the benefits and safety of exercise before beginning the intervention. Participants in the intradialytic group will perform supervised exercises during their dialysis sessions, while those in the pre-dialysis group will complete similar exercises before their dialysis sessions. Each participant will undergo the intervention twice per week for 12 weeks.
Primary outcomes include physical function, assessed using the Six-Minute Walk Test and the Five Times Sit-to-Stand Test. Secondary outcomes include hemoglobin levels, electrolyte balance, and health-related quality of life measured by the KDQOL questionnaire. The study will be conducted at Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis Center, Kuwait, following ethical approval from the Ministry of Health Research Ethics Committee.
The results are expected to inform best practices for integrating physical therapy into dialysis care to enhance the health, safety, and well-being of individuals undergoing hemodialysis.
Inclusion: Adults aged between 21 and 65 years; Diagnosed with end-stage renal disease (ESRD); Undergoing maintenance hemodialysis for at least 3 months; Medically stable and cleared by the nephrologist to participate in moderate physical exercise; Able to understand and follow verbal instructions and provide informed consent.
Exclusion: Uncontrolled hypertension, recent myocardial infarction, or unstable angina; Severe musculoskeletal, neurological, or cardiovascular disorders that limit physical activity; Active infection, fever, or open wounds; Recent hospitalization within the past month; Participation in any other structured exercise program within the last 3 months.