Effect of moderate red or white wine drinking on cell-released particles in the blood
Tests how a single serving of wine changes blood particles in healthy adults.
Plain-language title generated from the registry record
Registry title: Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.
Key facts
- Where
- Seville, SpainSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 35 and 36 years old?
Source: NCT07361887, who can take part
Where in Spain
- Av. de Sánchez Pizjuán, s/n, 41009 Sevilla Facultad de Medicina . Universidad de SevillaSeville, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Seville
- Trial code
- NCT07361887
- Record updated
- 23 January 2026
- Original description
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults. EVs are small particles released by cells that carry proteins, lipids, and genetic material, and play important roles in communication between cells. Participants will consume a single serving of red or white wine, and blood samples will be collected before and after consumption to study changes in the composition and function of EVs. The study will also assess how these EVs affect vascular, immune, and brain-related cells. The results are expected to improve our understanding of how moderate wine intake contributes to cardiovascular and brain health.Read full original descriptionShow less
Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults. EVs are small particles released by cells that carry proteins, lipids, and genetic material, and play important roles in communication between cells. Participants will consume a single serving of red or white wine, and blood samples will be collected before and after consumption to study changes in the composition and function of EVs. The study will also assess how these EVs affect vascular, immune, and brain-related cells. The results are expected to improve our understanding of how moderate wine intake contributes to cardiovascular and brain health.
Inclusion: Healthy adult men and women aged 35 to 65 years; Body Mass Index (BMI) between 18.5 and 29.9 kg/m²; Non-smokers or ex-smokers for at least 12 months; Moderate alcohol consumers, defined as ≤2 units/day for men and ≤1 unit/day for women; Normal fasting glucose and lipid profile at screening; Willing and able to refrain from alcohol, polyphenol-rich foods, and intense exercise for 48 hours before each study visit; Able to understand the study procedures and provide written informed consent.
Exclusion: Participation in another clinical or biomedical study within the previous 3 months; History or clinical evidence of cardiovascular, hepatic, renal, thyroid, gastrointestinal, or metabolic diseases (including diabetes, dyslipidemia, or hypertension); Known allergy or intolerance to wine, alcohol, or its components (e.g., sulfites); History of alcohol abuse or inability to abstain from alcohol outside the study context; Any condition judged by the investigators to limit compliance or increase study risk (e.g., psychiatric disorders, inability to adhere to fasting requirements); Use of medications or supplements known to affect glucose, lipid, or inflammatory metabolism (e.g., statins, corticosteroids, anti-inflammatory drugs); Pregnancy or breastfeeding; Recent blood donation (within the last 3 months) or planned blood donation during the study period; Major weight change (>5% of body weight) within the last 3 months; Reluctance to receive information about incidental health findings arising from the study.