Heart, Lung and Mood Health in People With Rheumatoid Arthritis
Follows adults with rheumatoid arthritis using heart scans, lung tests and questionnaires.
Plain-language title generated from the registry record
Registry title: Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
Key facts
- Where
- Aarhus, Esbjerg, and Herning, DenmarkSee the 4 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 75 years old?
Source: NCT07363980, who can take part
Where in Denmark
- Aarhus University HospitalAarhus, DenmarkNo longer taking part
- Esbjerg HospitalEsbjerg, DenmarkNo longer taking part
- Regional Hospital GødstrupHerning, DenmarkNo longer taking part
- Silkeborg Regional HospitalHerning, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Ellen Margrethe Hauge
- Trial code
- NCT07363980
- Record updated
- 3 February 2026
- Original description
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that includes comprehensive baseline and follow-up assessments at 3, 5, and 10 years. It comprises a main protocol and several optional modules, including a Cardiac Imaging Module, Biobanking Module, Pulmonary Module, and Anxiety and Depression Module.Read full original descriptionShow less
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that includes comprehensive baseline and follow-up assessments at 3, 5, and 10 years. It comprises a main protocol and several optional modules, including a Cardiac Imaging Module, Biobanking Module, Pulmonary Module, and Anxiety and Depression Module.
The study aims to advance understanding of cardiopulmonary and psychological comorbidities in rheumatoid arthritis, to improve early identification and management, and to enhance insights into underlying disease mechanisms-ultimately refining risk stratification and targeted prevention strategies.
The study includes 4,000 patients with rheumatoid arthritis enrolled through the Cardiac Imaging Module in the main protocol. Participants undergo coronary computed tomography angiography, pulmonary function testing, physical examination, questionnaires, and biobanking, supplemented by genetic, proteomic, metabolomic, and microbiome profiling.
Inclusion: Fulfill the ACR/EULAR-2010 criteria for rheumatoid arthritis; Attending or has attended at least one visit during the last two years in rheumatology outpatient clinic for diagnostic or monitoring purposes related to rheumatoid arthritis; Age 50-75 years.
Exclusion: Prior coronary atherosclerotic symptoms as defined by myocardial infraction, percutaneous coronary intervention, or coronary artery bypass grafting; Diagnosed with overlapping systemic autoimmune diseases other than secondary Sjogren's syndrome; Active cancer; Allergy to radiocontrast agents; Estimated glomerular filtration rate (eGFR) < 30 mL/min; BMI > 35 kg/m2; Persistent atrial fibrillation.