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Gaze Contingent Attentional Reinforcement in Major Depressive Disorder

Key facts

Where
Tel Aviv, IsraelSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07364981, who can take part

Where in Israel

  • Tel Aviv UniversityTel Aviv, IsraelNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Tel Aviv University
Trial code
NCT07364981
Record updated
23 January 2026
Original description
The main objective of this randomized controlled trial is to evaluate whether a gaze-contingent feedback task using negative reinforcement can serve as an effective attention-modification procedure and contribute to the treatment of Major Depressive Disorder (MDD).Read full original descriptionShow less

Gaze Contingent Attentional Reinforcement Treatment of MDD

The main objective of this randomized controlled trial is to evaluate whether a gaze-contingent feedback task using negative reinforcement can serve as an effective attention-modification procedure and contribute to the treatment of Major Depressive Disorder (MDD).

Inclusion: Primary diagnosis of MDD; MADRS>=7; Normal or corrected-t-normal vision.

Exclusion: Pharmacological treatment if not stabilized for at least three months or concurrent psychotherapy; Severe alcohol or cannabis use disorder, and/or any severity of other substance use disorder (exepct nicotine use); Current unstable or untreated medical illness; Current or past organic mental disorder, seizure or brain injury; Present or past psychosis, manic or hypomanic episode, PTSD; High suicidal ideation or behavior; Eye-tracking calibration difficulties; Post-ECT treatment.

ClinicalTrials.gov NCT07364981