A Questionnaire to Spot Inherited Cancer Risk in Children With Cancer
Tests a family questionnaire for finding inherited cancer risk in children and teens with cancer.
Plain-language title generated from the registry record
Registry title: Questionnaire on Congenital Cancer Signs Through Self-Assessment
Key facts
- Where
- Bern, SwitzerlandSee the site
Where in Switzerland
- Inselspital, Universitäts Kinderklinik (University Children's Hospital) BernBern, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Insel Gruppe AG, University Hospital Bern
- Trial code
- NCT07378423
- Record updated
- 1 May 2026
- Original description
This clinical trial tests whether a patient- and caregiver-completed questionnaire (QUOCCAS) can accurately help identify children and adolescents with cancer who may have an underlying cancer predisposition syndrome (CPS). The study will also evaluate whether providing families with an educational brochure before their clinic visit improves their understanding of genetics and their satisfaction with care.Read full original descriptionShow less
Questionnaire on Congenital Cancer Signs Through Self-Assessment (QUOCCAS)
This clinical trial tests whether a patient- and caregiver-completed questionnaire (QUOCCAS) can accurately help identify children and adolescents with cancer who may have an underlying cancer predisposition syndrome (CPS). The study will also evaluate whether providing families with an educational brochure before their clinic visit improves their understanding of genetics and their satisfaction with care.
The main questions it aims to answer are:
* Does QUOCCAS identify children at risk for CPS as accurately as physician-based tools and compared to genetic testing? * Does the Pre-Visit Preparation (PVP) brochure improve caregiver knowledge about genetics? * Does the PVP brochure improve caregiver satisfaction with the care and information they receive?
Participants will:
* Complete the QUOCCAS questionnaire about family history, clinical features, and cancer signs * Provide a blood or saliva sample for genetic testing (whole-exome or whole-genome sequencing) * Randomly receive or not receive the educational Pre-Visit Preparation brochure before completing the questionnaire * Complete brief surveys on their knowledge and satisfaction
Inclusion: The investigators will include newly diagnosed patients who received a cancer diagnosis included in the International Classification of Childhood Cancer version 3 (ICCC3) criteria, treated at participating hospitals.
Exclusion: Over 21 years of age.