Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis
Key facts
- Who runs it
- Ankara Training and Research Hospital
- Where
- Ankara, TürkiyeSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 86 people, planned
- Started
- 2 Feb 2026
- Planned end
- 1 Nov 2026
- Type of study
- Observational, 2 groups
- Treatments tested
- Perineural 5% Dextrose Injection
- Perineural Local Anesthetic Injection
- Record updated
- 9 September 2026
Who can take part
- Age
- 40 years to 65 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Symptomatic knee osteoarthritis
- Clinical/radiological diagnosis
- Knee pain ≥ 3 months
- Written informed consent
Who cannot take part
- Prior knee surgery
- Inflammatory rheumatic disease
- Severe systemic or neurological disease
- Recent intra-articular injection
- Pregnancy or breastfeeding
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 65 years old?
Where in Türkiye
- Ankara Training and Research Hospital Ankara, Altindag, Turkey, 06230Ankara, TürkiyeContact: Nadide Koca, M.D.Not yet recruiting
About the trial
What the trial wants to find out
This prospective observational study aims to compare the clinical effectiveness of perineural 5% dextrose injections and perineural local anesthetic injections in patients with symptomatic knee osteoarthritis. Adult patients receiving routine perineural injection therapy will be followed for six months. Pain intensity and functional outcomes will be assessed at baseline and at 1, 3, and 6 months after treatment using validated clinical assessment tools.
The 2 groups in the trial
- Perineural 5% Dextrose Group
Patients with symptomatic knee osteoarthritis receiving perineural 5% dextrose injections as part of routine clinical care.
Treatment: Perineural 5% Dextrose Injection
- Perineural Local Anesthetic Group
Patients with symptomatic knee osteoarthritis receiving perineural local anesthetic injections as part of routine clinical care.
Treatment: Perineural Local Anesthetic Injection
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Prospective Evaluation of the Clinical Effectiveness of Perineural Dextrose and Conventional Local Anesthetic Injections in Patients With Symptomatic Knee Osteoarthritis
- Fit questions
- Built from NCT07381621, who can take part
- Record updated
- 9 September 2026