Combined light and ultrasound therapy for nodular basal cell skin cancer
Tests light plus ultrasound treatment in adults with nodular basal cell skin cancer.
Plain-language title generated from the registry record
Registry title: Photodynamic Therapy Associated With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Key facts
- Where
- Jaú, BrazilSee the site
- Phase
- Phase 3
Where in Brazil
- Hospital Amaral CarvalhoJaú, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Sao Paulo
- Trial code
- NCT07381972
- Record updated
- 2 February 2026
- Original description
Evaluation of a therapeutic protocol based on the combination of photodynamic therapy and sonodynamic therapy, referred to as sonophotodynamic therapy. Since this new protocol is applied in a single day, it is called the single-visit Sono-PDT protocol. This protocol will be used for the treatment of nodular basal cell carcinoma lesions.Read full original descriptionShow less
Optimization of Photodynamic Therapy Through the Association With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Evaluation of a therapeutic protocol based on the combination of photodynamic therapy and sonodynamic therapy, referred to as sonophotodynamic therapy. Since this new protocol is applied in a single day, it is called the single-visit Sono-PDT protocol. This protocol will be used for the treatment of nodular basal cell carcinoma lesions.
Inclusion: Adults of both sexes, aged 18 years and older; Histologically confirmed nodular basal cell carcinoma with lesion diameter ≤1.0 cm; Participants with multiple lesions may be included, provided that each lesion meets all inclusion criteria.
Exclusion: Known hypersensitivity or allergy to methyl aminolevulinate (MAL) or any excipients of the study medication; Porphyria or other disorders of porphyrin metabolism; Presence of photosensitive diseases, including lupus erythematosus; Any condition that, in the investigator's opinion, would interfere with study participation or safety; Nodular basal cell carcinoma lesions >1.0 cm in diameter; Histological subtypes of infiltrative basal cell carcinoma, including micronodular, infiltrative, sclerodermiform (morpheaform), plano-cicatricial, or terebrant subtypes; Pregnant or breastfeeding women; Women of childbearing potential not using an acceptable method of contraception.