Under construction – not a live service
Sign in
Not yet recruitingNo phase

"The Importance of Adding Fenestration to Ultrasound-Guided Baker's Cyst Aspiration"

Key facts

Who runs it
Istanbul University - Cerrahpasa
Where
Türkiye1 site in 1 countryChoose a country to see its sites
Trial code
Status
Not yet recruiting
People taking part
44 people, planned
Started
15 Feb 2026
Planned end
30 May 2026
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Baker's Cyst Aspiration
  • Steroid-Lidocaine Injection
  • Ultrasound-Guided Fenestration
Record updated
4 February 2026

Who can take part

Age
40 years to 75 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 17 criteriaShow less

Who can take part

  • Adults aged 40 to 75 years
  • Diagnosis of knee osteoarthritis according to the 2010 American College of Rheumatology (ACR) criteria
  • Presence of a symptomatic Baker's cyst confirmed by ultrasonography
  • Ability to understand study procedures and provide written informed consent
  • Sufficient intellectual and social capacity to comply with study visits and follow-up requirements

Who cannot take part

  • Requirement to continue medications for inflammatory arthritis
  • Use of nonsteroidal anti-inflammatory drugs (NSAIDs) within the past 1 week
  • Physical therapy applied to the knee region within the past 1 month
  • Active systemic infection
  • History of malignancy
  • History of knee surgery
  • Contraindications to aspiration or corticosteroid injection (e.g., local infection, bleeding disorders, uncontrolled diabetes mellitus)
  • Diagnosed psychiatric disorder that may impair study participation
  • Presence of inflammatory arthritis, septic arthritis, crystal arthropathy, or secondary causes of knee osteoarthritis
  • Kellgren-Lawrence grade 4 knee osteoarthritis
  • Intra-articular knee injection within the past 3 months
  • Knee trauma within the past 3 months

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 75 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This study aims to evaluate whether adding a fenestration procedure to standard ultrasound-guided aspiration and corticosteroid-lidocaine injection provides additional clinical benefits for patients with symptomatic Baker's cyst associated with knee osteoarthritis. Baker's cyst is a fluid-filled swelling located behind the knee that may cause pain, stiffness, swelling, and limited mobility. Although aspiration with medication injection is commonly used to relieve symptoms, recurrence of the cyst is frequent.

Read full original descriptionShow less

Fenestration is a minimally invasive technique in which small controlled openings are created in the cyst wall under ultrasound guidance to improve internal drainage and potentially reduce recurrence. In this prospective, randomized, double-blind, controlled study, participants will be assigned to one of two groups:

1. aspiration with corticosteroid and lidocaine injection, or 2. aspiration with corticosteroid and lidocaine injection plus fenestration.

Pain, functional scores, cyst measurements, and recurrence will be assessed at follow-up visits at 2 weeks, 1 month, and 3 months. The purpose of this study is to determine whether the addition of fenestration results in better symptom improvement and lower rates of recurrence compared with standard aspiration alone.

The 2 groups in the trial

  • Aspiration + Steroid-LidocaineExisting treatment, for comparison

    Ultrasound-guided aspiration of Baker's cyst followed by injection of corticosteroid and lidocaine mixture. No fenestration is performed.

    Treatment: Baker's Cyst Aspiration and Steroid-Lidocaine Injection

  • Arm Title: Aspiration + Steroid-Lidocaine + FenestrationTreatment being tested

    Ultrasound-guided aspiration followed by corticosteroid-lidocaine injection and fenestration using multiple needle perforations under real-time ultrasound guidance.

    Treatment: Baker's Cyst Aspiration, Steroid-Lidocaine Injection, and Ultrasound-Guided Fenestration

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Fit questions
Built from NCT07385560, who can take part
Record updated
4 February 2026