"The Importance of Adding Fenestration to Ultrasound-Guided Baker's Cyst Aspiration"
Key facts
- Who runs it
- Istanbul University - Cerrahpasa
- Where
- Istanbul, TürkiyeSee the site
- Trial code
- Status
- Not yet recruiting
- People taking part
- 44 people, planned
- Started
- 15 Feb 2026
- Planned end
- 30 May 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Baker's Cyst Aspiration
- Steroid-Lidocaine Injection
- Ultrasound-Guided Fenestration
- Record updated
- 4 February 2026
Who can take part
- Age
- 40 years to 75 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- Adults aged 40 to 75 years
- Diagnosis of knee osteoarthritis according to the 2010 American College of Rheumatology (ACR) criteria
- Presence of a symptomatic Baker's cyst confirmed by ultrasonography
- Ability to understand study procedures and provide written informed consent
- Sufficient intellectual and social capacity to comply with study visits and follow-up requirements
Who cannot take part
- Requirement to continue medications for inflammatory arthritis
- Use of nonsteroidal anti-inflammatory drugs (NSAIDs) within the past 1 week
- Physical therapy applied to the knee region within the past 1 month
- Active systemic infection
- History of malignancy
- History of knee surgery
- Contraindications to aspiration or corticosteroid injection (e.g., local infection, bleeding disorders, uncontrolled diabetes mellitus)
- Diagnosed psychiatric disorder that may impair study participation
- Presence of inflammatory arthritis, septic arthritis, crystal arthropathy, or secondary causes of knee osteoarthritis
- Kellgren-Lawrence grade 4 knee osteoarthritis
- Intra-articular knee injection within the past 3 months
- Knee trauma within the past 3 months
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 75 years old?
Where in Türkiye
- Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Department of Physical Medicine and RehabilitationIstanbul, TürkiyeContact: Tutku Naz bulut, MDNo longer taking part
About the trial
What the trial wants to find out
This study aims to evaluate whether adding a fenestration procedure to standard ultrasound-guided aspiration and corticosteroid-lidocaine injection provides additional clinical benefits for patients with symptomatic Baker's cyst associated with knee osteoarthritis. Baker's cyst is a fluid-filled swelling located behind the knee that may cause pain, stiffness, swelling, and limited mobility. Although aspiration with medication injection is commonly used to relieve symptoms, recurrence of the cyst is frequent.
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Fenestration is a minimally invasive technique in which small controlled openings are created in the cyst wall under ultrasound guidance to improve internal drainage and potentially reduce recurrence. In this prospective, randomized, double-blind, controlled study, participants will be assigned to one of two groups:
1. aspiration with corticosteroid and lidocaine injection, or 2. aspiration with corticosteroid and lidocaine injection plus fenestration.
Pain, functional scores, cyst measurements, and recurrence will be assessed at follow-up visits at 2 weeks, 1 month, and 3 months. The purpose of this study is to determine whether the addition of fenestration results in better symptom improvement and lower rates of recurrence compared with standard aspiration alone.
The 2 groups in the trial
- Aspiration + Steroid-LidocaineExisting treatment, for comparison
Ultrasound-guided aspiration of Baker's cyst followed by injection of corticosteroid and lidocaine mixture. No fenestration is performed.
Treatment: Baker's Cyst Aspiration and Steroid-Lidocaine Injection
- Arm Title: Aspiration + Steroid-Lidocaine + FenestrationTreatment being tested
Ultrasound-guided aspiration followed by corticosteroid-lidocaine injection and fenestration using multiple needle perforations under real-time ultrasound guidance.
Treatment: Baker's Cyst Aspiration, Steroid-Lidocaine Injection, and Ultrasound-Guided Fenestration
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT07385560, who can take part
- Record updated
- 4 February 2026