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Exercise in people with reduced lung function, and its effect on later COPD

Tests exercise, with and without telehealth, in people with PRISm lung function.

Plain-language title generated from the registry record
Registry title: Role of Exercise in PRISm and Subsequent Development of COPD

Key facts

Where
Hong Kong, ChinaSee the site

Where in China

  • The University of Hong Kong, Queen Mary HospitalHong Kong, ChinaTaking people

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  2. Are travel costs paid?
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Trial details

Who runs it
The University of Hong Kong
Trial code
NCT07387432
Record updated
6 March 2026
Original description
Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted.Read full original descriptionShow less

Role of Exercise in Functional Capacity of Smokers and Subsequent Development of Chronic Obstructive Pulmonary Disease

Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted.

While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.

Inclusion: Age 18 or above; Smoker/ ex-smoker; Spirometry shows PRISm, with FEV1/FVC >= 0.7 and FEV1 <80% predicted; Ambulatory to walk; Able to give informed consent.

Exclusion: Age below 18; Non-smoker; Spirometry does not show PRISm/ unable to perform spirometry; Requires assistance for walking; Unable to give informed consent.

ClinicalTrials.gov NCT07387432