Screening Relatives of Brain Bleed Patients for Unruptured Brain Aneurysms
Checks close relatives of people with brain bleeding for unruptured aneurysms using brain scans.
Plain-language title generated from the registry record
Registry title: Screening in Relatives With Elevated Risk for Unruptured Intracranial Aneurysms
Key facts
- Where
- Novi Sad, SerbiaSee the site
Where in Serbia
- University Clinical Center of VojvodinaNovi Sad, SerbiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Novi Sad
- Trial code
- NCT07387575
- Record updated
- 4 February 2026
- Original description
The purpose of this study is to screen first-degree relatives of patients with aneurysmal subarachnoid hemorrhage using magnetic resonance angiography to detect unruptured intracranial aneurysms. This study aims to identify individuals who are at increased risk and determine the effect of environmental factors for development of unruptured intracranial aneurysms.Read full original descriptionShow less
Screening for Intracranial Unruptured Aneurysms in First-Degree Relatives of Patients With Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to screen first-degree relatives of patients with aneurysmal subarachnoid hemorrhage using magnetic resonance angiography to detect unruptured intracranial aneurysms. This study aims to identify individuals who are at increased risk and determine the effect of environmental factors for development of unruptured intracranial aneurysms.
Inclusion: First-degree relatives (parents, siblings, or children) of patients diagnosed with aneurysmal subarachnoid hemorrhage (aSAH); Age ≥ 30 years at the time of enrollment, and current cigarette smokers or diagnosed with hypertension (either treated or untreated); Able and willing to undergo magnetic resonance angiography (MRA); Able to provide written informed consent; 6. Sporadic aneurysm subjects must have a confirmed UIAs.
Exclusion: History of intracranial aneurysm rupture or prior subarachnoid hemorrhage; Contraindications to MRI/MRA (e.g., pacemaker, metallic implants, severe claustrophobia) or pregnancy (due to MRI safety considerations); A history of polycystic kidney disease, Marfan's Syndrome, Ehlers Danlos Syndrome, or fibromuscular dysplasia; Unable or unwilling to provide informed consent; Participation in another interventional study that could interfere with outcomes.