Effect of taking many medicines on healthy aging in older people with HIV
Looks at how many medicines affect healthy aging in people with HIV over 75.
Plain-language title generated from the registry record
Registry title: Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75
Key facts
- Where
- Nice, FranceSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people living with HIV who are 75 or older. It studies how taking many medicines affects healthy aging.
- Age
- 75 years or older
- Sex
- All sexes can join.
- Biomarker or test result
- HIV-positive
Main reasons for not taking part
- Refusing to take part
- Known severe memory or thinking problems that prevent the interview
- Being under guardianship or conservatorship
This trial only enrols participants living with HIV. The registry sentence this rests on: HIV-positive
Read by machine on 12 November 2026.
Where in France
- CHU de NiceNice, FranceContact: Lysandre BLANCKEMANTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Centre Hospitalier Universitaire de Nice
- Trial code
- NCT07388394
- Record updated
- 29 October 2026
- Original description
Since the advent of antiretroviral treatments, the life expectancy of people living with HIV (PLHIV) has increased significantly. In France, more than 30% of PLHIV are now over 50 years old. This population is exposed to high multimorbidity, leading to frequent polypharmacy, defined as the regular use of at least five medications. Polypharmacy also has a qualitative dimension, including potentially inappropriate prescriptions. It increases the risk of adverse effects and drug interactions and impairs quality of life. A coordinated geriatric approach is therefore essential to optimize care. Healthy aging, promoted by the WHO, aims to improve the lives of older people. In this context, a study will be conducted at the Nice University Hospital among PLHIV aged 75 and over. It will collect quantitative data, the results of which will enable us to consider, if necessary, adapting the care pathways of these patients whose needs are complex.Read full original descriptionShow less
Describe and Evaluate the Impact of Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75 Who Are Being Treated at Nice University Hospital.
Since the advent of antiretroviral treatments, the life expectancy of people living with HIV (PLHIV) has increased significantly. In France, more than 30% of PLHIV are now over 50 years old. This population is exposed to high multimorbidity, leading to frequent polypharmacy, defined as the regular use of at least five medications. Polypharmacy also has a qualitative dimension, including potentially inappropriate prescriptions. It increases the risk of adverse effects and drug interactions and impairs quality of life. A coordinated geriatric approach is therefore essential to optimize care. Healthy aging, promoted by the WHO, aims to improve the lives of older people. In this context, a study will be conducted at the Nice University Hospital among PLHIV aged 75 and over. It will collect quantitative data, the results of which will enable us to consider, if necessary, adapting the care pathways of these patients whose needs are complex.
Inclusion: HIV-positive; Aged 75 or over; Affiliated with the social security system; Having expressed no objection to participating in the study.
Exclusion: Known severe cognitive impairment preventing the interview from being conducted; Refusal to participate; Patient under guardianship or conservatorship.