Studies movement and sensing skills in people with autism and their families
Looks at movement and sensory skills in autistic children, their siblings and parents.
Plain-language title generated from the registry record
Registry title: Characterization of (A)Typical Sensorimotor Pathways in Individuals With Autism
Key facts
- Where
- Bosisio Parini, ItalySee the site
Where in Italy
- IRCCS E. MedeaBosisio Parini, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS Eugenio Medea
- Trial code
- NCT07389720
- Record updated
- 5 February 2026
- Original description
The goal of this interventional study is to understand whether sensorimotor skills could represent an endophenotype for autism, i.e. a specific class of biomarkers that bridges the gap between biological components of a condition and the behavioral/clinical dimensions. Motor and sensory differences are often observed in people with autism and may appear early in development or be shared among family members.Read full original descriptionShow less
Characterization of (A)Typical Sensorimotor Pathways in Individuals With Autism
The goal of this interventional study is to understand whether sensorimotor skills could represent an endophenotype for autism, i.e. a specific class of biomarkers that bridges the gap between biological components of a condition and the behavioral/clinical dimensions. Motor and sensory differences are often observed in people with autism and may appear early in development or be shared among family members.
The study will address three main questions:
* What are the developmental effects of early differences in motor and sensory skills? * Are motor and sensory abilities influenced by family relationships? * Can studying motor and sensory differences in autism help researchers better understand the biological mechanisms underlying the condition? This study is structured in three topic-oriented work packages (WPs): WP1, a longitudinal assessment of sensorimotor skills as early predictors of later social characteristics in a mixed sample of infant siblings of autistic children (at elevated likelihood of autism) or with typical familial likelihood (no first-degree relatives with autism) (Q1); WP2, a cross-sectional investigation of sensorimotor abilities in autistic children and their parents as compared with typically developing children and their parents (Q2); and WP3, a dense-phenotyping approach to establish, within individuals, associations between traits across behavioral, neural, and molecular levels.
Inclusion: children aged 2 to 12 years (both autistic and typically developing); Clinical diagnosis of Autism Spectrum Disorder based on clinical judgment according to DSM-5 criteria (for the autism group); being parents of the enrolled children (both autistic and typically developing); infants younger than 24 months of age with a first-degree family member with a clinical diagnosis of Autism Spectrum Disorder.
Exclusion: Current use of medications and/or psychotropic drugs; Presence of medical and/or neurological conditions of clinical significance, including epilepsy; Presence of dysmorphic syndromes or known genetic syndromes.