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Using face and speech video analysis to tell Parkinson's from similar disorders

Studies face and speech video of people with Parkinson's and similar conditions.

Plain-language title generated from the registry record
Registry title: Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

Key facts

Where
Beijing, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with Parkinson's disease, multiple system atrophy (MSA-P) or progressive supranuclear palsy (PSP), and healthy controls. Facial expression videos and speech recordings are used to study digital markers.

Age
18-75 years old for the patient groups. The registry lists 15 to 75 years overall.
Sex
All sexes can join.
Disease stage
Parkinson's disease: early stage (Hoehn-Yahr score ≤ 2.5) or mid-to-late stage (Hoehn-Yahr score 2.5-5). Also people with MSA-P or PSP who meet the named diagnostic criteria.

Main reasons for not taking part

  • History of stroke or other brain blood vessel disease, head injury, hydrocephalus, brain tumor, or brain surgery
  • Metal implants, cardiac pacemakers, or other metal foreign bodies (Parkinson's patients)
  • Severe involuntary movements in Parkinson's patients that would stop them cooperating with video or audio recording
  • Mini-Mental State Examination (MMSE) score ≤ 24 points

Read by machine on 13 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 15 and 75 years old?

Source: NCT07392411, who can take part

Where in China

  • BeijingHospital not named in the registryContact: Lingyan ma Jennifer, M.D.Taking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Beijing Tiantan Hospital
Trial code
NCT07392411
Record updated
6 February 2026
Original description
This research employs AI to analyze facial expressions and speech patterns, aiming to develop new digital tools for diagnosing and differentiating Parkinson's disease and similar disorders.Read full original descriptionShow less

Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

This research employs AI to analyze facial expressions and speech patterns, aiming to develop new digital tools for diagnosing and differentiating Parkinson's disease and similar disorders.

Inclusion: Inclusion Criteria for Parkinson's Disease (PD) Group: (1) Diagnostic Criteria: Meet the diagnostic criteria for Parkinson's disease established by the Movement Disorder Society (MDS) in 2015. (2) Age Range: 18-75 years old. (3) Disease Severity: Early-stage PD: Hoehn-Yahr score ≤ 2.5 points. Mid-to-late-stage PD: Hoehn-Yahr score 2.5-5 points. (4) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording. (5) Informed Consent: Signed informed consent form; Inclusion Criteria for Parkinson's Plus Syndromes (MSA-P, PSP) Group: (1) Age Range: 18-75 years old. (2) Diagnostic Criteria: MSA patients must meet the diagnostic criteria established by the [Chinese Expert Consensus on the Diagnosis of Multiple System Atrophy, 2017]. PSP patients must meet the diagnostic criteria established by the [Chinese Clinical Diagnostic Criteria for Progressive Supranuclear Palsy, 2016 Edition]. (3) Consent for Data Collection: Willing to undergo facial expression video and speech audio recording. (4) Informed Consent: Signed informed consent form.

Exclusion: History of cerebrovascular disease, head trauma, hydrocephalus, brain tumors, or intracranial surgery; Presence of metal implants, cardiac pacemakers, or other metallic foreign bodies (applies to PD patients); Severe dyskinesia in PD patients that would compromise cooperation with video/audio recording; Mini-Mental State Examination (MMSE) score ≤ 24 points.

ClinicalTrials.gov NCT07392411