Genetic Testing and Education for Alcohol Flushing in East Asian American Adults
Tests whether genetic testing plus education helps East Asian American adults who flush when drinking.
Plain-language title generated from the registry record
Registry title: ALDH2 Genetic Testing in East Asian Community
Key facts
- Where
- Chicago, United StatesSee the site
Where in United States
- Northwestern University Feinberg School of MedicineChicago, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Northwestern University
- Trial code
- NCT07392775
- Record updated
- 28 October 2026
- Original description
The goal of this clinical trial is to learn whether education plus genetic testing for ALDH2*2 and ADH1B*2 is feasible and acceptable and whether it influences modifiable health behaviors in East Asian American adults who experience alcohol flushing when they drink alcohol or have a family history of flushing. The main questions it aims to answer are:Read full original descriptionShow less
A Community-Based Approach for ALDH2 Genetic Testing in East Asian Americans
The goal of this clinical trial is to learn whether education plus genetic testing for ALDH2*2 and ADH1B*2 is feasible and acceptable and whether it influences modifiable health behaviors in East Asian American adults who experience alcohol flushing when they drink alcohol or have a family history of flushing. The main questions it aims to answer are:
1. Is providing education plus ALDH2*2/ADH1B*2 genetic testing feasible and acceptable in a clinical care context? 2. Does receiving genetic testing results plus education lead to changes in modifiable health behaviors compared with education alone? Researchers will compare education plus genetic testing (intervention arm) to education only (control arm) to see if adding genetic testing improves feasibility/acceptability and supports health behavior change.
Participants will:
1. Complete an education module about alcohol flushing and ALDH2/ADH1B 2. Be randomized to either: (A) Receive genetic testing for ALDH2*2 and ADH1B*2 with results disclosure, or (B) Receive education only. 3. Complete follow-up measures about feasibility, acceptability, and modifiable health behaviors
Inclusion: Age 18 or older; Self-identified as East Asian and/or East Asian American; Flush when they drink alcohol or have a family member who flushes when they drink; Able to read and speak English.