Wound Suction Dressing After Emergency Abdominal Surgery in People With Insulin-Treated Diabetes
Tests a suction wound dressing to prevent infection after abdominal surgery in people with diabetes.
Plain-language title generated from the registry record
Registry title: Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds
Key facts
- Where
- Budapest, HungarySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with diabetes who need urgent open abdominal surgery and are at high risk of wound infection after the operation.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Diabetes that is already known or newly found at admission. Urgent open abdominal surgery (laparotomy) with a high risk of surgical site infection, in cleanliness category III-IV.
Main reasons for not taking part
- Pregnancy
- Cancer that has spread and cannot be removed, or cancer spread within the abdominal lining
- Life expectancy of less than 30 days
- Refusal to take part in the study
Read by machine on 9 November 2026.
Where in Hungary
- Semmelweis University, Department of Surgery, Transplantation and GastroenterologyBudapest, HungaryNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Semmelweis University
- Trial code
- NCT07392853
- Record updated
- 6 February 2026
- Original description
The aim of this study is to evaluate the effectiveness of prophylactic Negative Pressure Wound Therapy (NPWT) in patients with diabetes mellitus undergoing laparotomy who are at high risk for Surgical Site Infections (SSI). In addition to clinical efficacy, the investigators also plan a cost effectiveness analysis to assess the applicability of this relatively high-cost intervention in a domestic healthcare setting.Read full original descriptionShow less
Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds - A Randomized, Prospective Clinical Trial
The aim of this study is to evaluate the effectiveness of prophylactic Negative Pressure Wound Therapy (NPWT) in patients with diabetes mellitus undergoing laparotomy who are at high risk for Surgical Site Infections (SSI). In addition to clinical efficacy, the investigators also plan a cost effectiveness analysis to assess the applicability of this relatively high-cost intervention in a domestic healthcare setting.
Inclusion: Age ≥18 years,; Undergoing urgent abdominal surgery,; Diagnosis of diabetes mellitus either already present or newly diagnosed at admission; High SSI risk. We consider a patient to be at high SSI risk if the operating surgeon categorizes the patient as high risk, and the patient is classified in the III-IV cleanliness category with an open abdominal surgical procedure (laparotomy). "High SSI risk" may also be assessed individually based on existing severe risk factors or using an SSI risk calculator (patients with a normal laparotomy SSI risk more than 3 times the baseline are eligible).
Exclusion: Disseminated cancer (irresectable distant metastasis, peritoneal carcinomatosis),; Pregnancy,; Life expectancy of less than 30 days,; Refusal to participate in the study.