Tracking Recovery After Pelvic Exenteration Surgery for Rectal Cancer
Follows adults with advanced or recurrent rectal cancer undergoing pelvic exenteration surgery.
Plain-language title generated from the registry record
Registry title: Postoperative Results and Outcomes in Surgical Pelvic Exenteration
Key facts
- Where
- Taoyuan, TaiwanSee the site
Where in Taiwan
- Chang Gung Memorial Hospital, LinkouTaoyuan, TaiwanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chang Gung Memorial Hospital
- Trial code
- NCT07395505
- Record updated
- 9 February 2026
- Original description
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs. When cancer invades adjacent structures (such as the sacrum, bladder, or prostate), a complex procedure called pelvic exenteration (PE) is often required to remove the tumor entirely.Read full original descriptionShow less
From Cure to Quality: Advancing Surgical and Postoperative Outcomes in Pelvic Exenteration
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs. When cancer invades adjacent structures (such as the sacrum, bladder, or prostate), a complex procedure called pelvic exenteration (PE) is often required to remove the tumor entirely.
This research does not involve testing new or experimental surgical techniques. All procedures performed in this study are part of standard clinical practice. Instead, the focus of this project is to:
Standardize Procedures: Create consistent, high-quality steps for the surgical team to follow.
Improve Teamwork: Enhance coordination between different medical specialists (such as colorectal surgeons, urologists, and oncologists) to provide better care.
Track Outcomes: Use a patient registry to monitor clinical data and quality of life after surgery through patient-reported surveys.
A total of 24 adult patients will be enrolled over a three-year period. By refining these workflows and monitoring patient recovery, the study aims to ensure that these complex surgeries are performed as safely and effectively as possible.
Inclusion: Adult patients aged ≥20 years; Histologically confirmed rectal adenocarcinoma or anal adenocarcinoma; Tumor invasion of sacrum (requiring sacrectomy, S2-S4) or anterior structures (e.g., prostate), or lateral structures(SLAM, vessels, nerve) where resection of the invaded organ is necessary to achieve R0 resection, as determined by MDT; Surgical candidacy confirmed by multidisciplinary review (colorectal surgery, urology, orthopedics, oncology, radiology, pathology); Preoperative imaging (MRI, PET/CT) confirming resectable disease without distant metastasis; Signed informed consent obtained.
Exclusion: Severe comorbidities rendering major surgery or anesthesia unsafe; Unresectable disease or widespread distant metastasis; Patients unable to complete postoperative follow-up or unwilling to participate in PROMs assessment.