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Linking ultrasound findings of adenomyosis to symptoms in women

Compares uterine ultrasound findings with symptoms in women who may have adenomyosis.

Plain-language title generated from the registry record
Registry title: Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms

Key facts

Where
Basel and Winterthur, SwitzerlandSee the 2 sites

Where in Switzerland

  • University Hospital BaselBasel, SwitzerlandTaking people
  • Kantonsspital WinterthurWinterthur, SwitzerlandTaking people

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Trial details

Who runs it
Swiss GO Trial Group
Trial code
NCT07397715
Record updated
16 October 2026
Original description
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis assessing disease severity. Consecutive pre- and perimenopausal symptomatic and asymptomicasymptomatic women with an uterus presenting for gynaecological ultrasound exams will be asked to participate in the study. Routine gynecologicalgynaecological ultrasound exams will be performed and study participants will fill out a questionnaire on their symptoms (if any) and bleeding pattern. There will be one visit and no interventions.Read full original descriptionShow less

Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms (MUSA 3)

The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis assessing disease severity. Consecutive pre- and perimenopausal symptomatic and asymptomicasymptomatic women with an uterus presenting for gynaecological ultrasound exams will be asked to participate in the study. Routine gynecologicalgynaecological ultrasound exams will be performed and study participants will fill out a questionnaire on their symptoms (if any) and bleeding pattern. There will be one visit and no interventions.

Inclusion: Women of pre- and perimenopausal age presenting for gynaecologic ultrasound exam giving voluntary informed written consent; Symptomatic and asymptomatic women; Patients with hormonal contraceptives and Hormone Replacement Therapy (HRT) can be included, but information will be noted.

Exclusion: Prior myomectomy for FIGO 3-6 fibroids; Prior history of diagnosed intraabdominal adhesions (surgery); Prior diagnosis of pelvic congestion syndrome; Prior surgery or treatment for deep infiltrating endometriosis; Any serious underlying medical, psychiatric or psychological condition, which may interfere with the patient's capacity of discernment; History of pelvic urogynaecologic surgery (TVT, mesh surgery, etc.); Malignancy or premalignancy of uterus/cervix; Patients with coagulation disorders under current anticoagulation medication; Psychiatric disease precluding a reliable estimation of pain; Acute of chronic pelvic infection (cervicitis, endometritis, salpingitis, frozen pelvis); Missing written consent (study consent); Postmenopausal women; Pregnancy; Acute other symptoms:; Urinary symptoms (dysuria, urgency, grade III stress incontinence); Ovarian lesions; Sonographic signs of deep infiltrating endometriosis (DIE); Intracavitary pathology (Fibroid 0-2, polyp, adhesions); Retained products of conception; >3 small fibroids below 2 cm in largest diameter FIGO 3-8 (i.e. the presence of three fibroids below 2cm is NOT considered an exclusion criterion); Presence of any fibroid >2cm.

ClinicalTrials.gov NCT07397715