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Linking ultrasound findings of adenomyosis to symptoms in women

Compares uterine ultrasound findings with symptoms in women who may have adenomyosis.

Key facts

Who runs it
Swiss GO Trial Group
Where
Barcelona, SpainSee the siteAlso in 3 other countries, 4 sites
Trial code
Registry title
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
Status
Recruiting
People taking part
1,000 people, planned
Started
15 Mar 2024
Expected to end
1 Feb 2029
Type of study
Observational
Record updated
16 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women before or around menopause who come for a gynaecological ultrasound exam, with or without symptoms. It studies ultrasound signs of adenomyosis and symptoms.

Age
18 Years or older, before or around menopause
Sex
Women only
Earlier treatment
Women using hormonal contraceptives or hormone replacement therapy can join, but this will be noted.

Main reasons for not taking part

  • Postmenopausal women
  • Pregnancy
  • Cancer or pre-cancer of the uterus or cervix
  • Any fibroid larger than 2cm (0.8 in), or more than 3 small fibroids
  • Signs of deep infiltrating endometriosis or prior surgery or treatment for it

The registry criteria, word for word

Show all 24 criteriaShow less

Who can take part

  • Women of pre- and perimenopausal age presenting for gynaecologic ultrasound exam giving voluntary informed written consent
  • Symptomatic and asymptomatic women
  • Patients with hormonal contraceptives and Hormone Replacement Therapy (HRT) can be included, but information will be noted

Who cannot take part

  • Prior myomectomy for FIGO 3-6 fibroids
  • Prior history of diagnosed intraabdominal adhesions (surgery)
  • Prior diagnosis of pelvic congestion syndrome
  • Prior surgery or treatment for deep infiltrating endometriosis
  • Any serious underlying medical, psychiatric or psychological condition, which may interfere with the patient's capacity of discernment
  • History of pelvic urogynaecologic surgery (TVT, mesh surgery, etc.)
  • Malignancy or premalignancy of uterus/cervix
  • Patients with coagulation disorders under current anticoagulation medication
  • Psychiatric disease precluding a reliable estimation of pain
  • Acute of chronic pelvic infection (cervicitis, endometritis, salpingitis, frozen pelvis)
  • Missing written consent (study consent)
  • Postmenopausal women
  • Pregnancy
  • Acute other symptoms:
  • Urinary symptoms (dysuria, urgency, grade III stress incontinence)
  • Ovarian lesions
  • Sonographic signs of deep infiltrating endometriosis (DIE)
  • Intracavitary pathology (Fibroid 0-2, polyp, adhesions)
  • Retained products of conception
  • >3 small fibroids below 2 cm in largest diameter FIGO 3-8 (i.e. the presence of three fibroids below 2cm is NOT considered an exclusion criterion)
  • Presence of any fibroid >2cm

Where in Spain

Also in 3 other countries, 4 sites

  • Hospital Universitari DexeusBarcelona, SpainContact: Betlem Graupera, Dr medTaking people

About the trial

What the trial wants to find out

The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis assessing disease severity. Consecutive pre- and perimenopausal symptomatic and asymptomicasymptomatic women with an uterus presenting for gynaecological ultrasound exams will be asked to participate in the study. Routine gynecologicalgynaecological ultrasound exams will be performed and study participants will fill out a questionnaire on their symptoms (if any) and bleeding pattern. There will be one visit and no interventions.

The group in the trial

  • Women with a uterus

    Pre - and perimenopausal women with a uterus that are scheduled for a gynaecologic ultrasound exam.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms (MUSA 3)
Plain-language title
Linking ultrasound findings of adenomyosis to symptoms in womenGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Record updated
16 October 2026