Studies TREX1 gene changes in people with systemic lupus erythematosus
Looks at TREX1 gene variants in adults with lupus and their effects on symptoms.
Plain-language title generated from the registry record
Registry title: " TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus
Key facts
- Where
- Qina, EgyptSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07397728, who can take part
Where in Egypt
- Qina University hospital, South Valley University HospitalQina, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- South Valley University
- Trial code
- NCT07397728
- Record updated
- 9 February 2026
- Original description
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.Read full original descriptionShow less
TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus: A Genotype-Phenotype Correlation Study
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.
Inclusion: Adult aged 18-60 years; Diagnosed as SLE per 2019 EULAR/ACR classification criteria; Presence of at least one cutaneous manifestation (acute, subacute, or chronic); Willing to provide written informed consent for participation and genetic testing.
Exclusion: Use of biologic therapy or immunosuppressive pulses within one month; Overlap autoimmune syndromes (e.g., dermatomyositis, systemic sclerosis); Systemic infection, malignancy, or pregnancy.