Using Speech Recordings From a Phone App to Estimate Relapse Risk in Psychosis
Studies whether weekly speech recordings can help estimate relapse risk in people with psychosis.
Plain-language title generated from the registry record
Registry title: Speech-based Assessment of Relapse Risk in People With Psychosis
Key facts
- Where
- Izmir, TürkiyeSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07397975, who can take part
Where in Türkiye
- Dokuz Eylul UniversityIzmir, TürkiyeNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Philipp Homan
- Trial code
- NCT07397975
- Record updated
- 9 February 2026
- Original description
This observational, multinational study assesses the feasibility of speech and self-report data collection across six languages for Artificial Intelligence (AI)-driven relapse risk estimation in psychosis. Over 12 months, patients at risk of relapse and healthy controls will provide weekly speech recordings and self-report data for automated analysis. Risk scores will be stored but not shared with treating clinicians. Independent clinical evaluations ensure data quality and validation. The study lays the foundation for future Clinical Decision Support System (CDSS) research and explores novel speech markers for relapse prediction while minimizing participant burden.Read full original descriptionShow less
A Prospective Multicenter Study for Relapse Risk Assessment Through Language Analysis in Individuals With Psychosis
This observational, multinational study assesses the feasibility of speech and self-report data collection across six languages for Artificial Intelligence (AI)-driven relapse risk estimation in psychosis. Over 12 months, patients at risk of relapse and healthy controls will provide weekly speech recordings and self-report data for automated analysis. Risk scores will be stored but not shared with treating clinicians. Independent clinical evaluations ensure data quality and validation. The study lays the foundation for future Clinical Decision Support System (CDSS) research and explores novel speech markers for relapse prediction while minimizing participant burden.
Healthy participants Inclusion Criteria:; Between 18 and 65 years old; Subjects must be able to provide informed consent (IC); Participants must have provided signed informed consent prior to enrollment; Participants should not take prescription drugs regularly; Native or equivalent fluency in speaking and understanding one of the following languages: English, German, Dutch, French, Czech or Turkish; Ability to have access to a smartphone and be capable of using a mobile app for speech-based data collection; Must be able to comply with the study schedule and procedures; Healthy participants Exclusion Criteria:; Any history of major diseases (e.g., cardiovascular, neurological, metabolic, renal, hepatic, respiratory or speech disorders); Recreational drug use or psychiatric disorders due to use of alcohol; Depression, anxiety, or other psychiatric disorders; Family history of depression, anxiety, or other psychiatric disorders; Individuals who are not able or willing to understand the purpose and details of the study; Individuals with psychosis Inclusion Criteria:; Between 18 and 65 years old; Diagnoses include psychotic disorders (schizophrenia, schizoaffective disorder, schizophreniform disorder, acute psychosis, bipolar disorder with psychotic symptoms, psychosis not otherwise specified); First visit must be during remission phase (baseline measurement); Current positive symptoms rated 3 (mild) or lower on all of these Brief Psychiatric Symptom Scale (BPRS) items: hallucinatory behavior, unusual thought content, conceptual disorganization; Must be able to comply with the study schedule and procedures; Subjects must be able to provide IC; Participants must have provided signed informed consent prior to enrollment; Native or equivalent fluency in speaking and understanding one of the following languages: English, German, Dutch, French, Czech or Turkish; Ability to have access to a smartphone and be capable of using a mobile app for speech-based data collection; Individuals with psychosis Exclusion Criteria:; Severe comorbid speech disorders (aphasia or severe stuttering) that prevent adequate speech recording; Individuals who are not able or willing to understand the purpose and details of the investigation; Citizens with psychiatric or somatic comorbidity, drug- or alcohol abuse will be allowed to participate, so that the sample will reflect the general population of citizens with psychosis and the study's endpoints will be generalizable.